Ugd

• Description: UDP-glucose dehydrogenase
  
  

Gene name	ywqF
Synonyms
Essential	no
Product	UDP-glucose dehydrogenase
Function	unknown
MW, pI	47 kDa, 5.03
Gene length, protein length	1320 bp, 440 aa
Immediate neighbours	ywqG, ptpZ
Gene sequence (+200bp)	Protein sequence
Genetic context

The gene

Basic information

• Coordinates:

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: UDP-glucose + 2 NAD+ + H2O = UDP-glucuronate + 2 NADH + 2 H+

• Protein family:

• Paralogous protein(s): TuaD, YtcA

Extended information on the protein

• Kinetic information:

• Domains:

• Modification: phosphorylation on Tyr-70 by PtkA PubMed

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• Swiss prot entry:

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: tkmA-ptkA-ptpZ-ywqF PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

1. Mijakovic I, Poncet S, Boël G, Mazé A, Gillet S, Decottignies P, Grangeasse C, Jamet E, Doublet P, Le Maréchal P, Deutscher J (2003) Transmembrane modulator-dependent bacterial tyrosine kinase activates UDP-glucose dehydrogenases. EMBO J 22:4709-4718. PubMed
2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed