YhaM

• Description: RNase, 3'-> 5' exoribonuclease
  
  

Gene name	yhaM
Synonyms
Essential	no
Product	RNase YhaM
Function	RNA degradation
Gene expression levels in SubtiExpress: yhaM
MW, pI	35 kDa, 5.851
Gene length, protein length	942 bp, 314 aa
Immediate neighbours	sbcE, yhaL
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

Rnases

This gene is a member of the following regulons

LexA regulon

The gene

Basic information

• Locus tag: BSU09930

Database entries

• BsubCyc: BSU09930

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: 3'-5' exoribonuclease

• Protein family: OB DNA-binding domain (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:
  • cytoplasm (Homogeneous) PubMed

Database entries

• BsubCyc: BSU09930

• Structure:

• UniProt: O07521

• KEGG entry: [3]

• E.C. number:

Additional information

• subject to Clp-dependent proteolysis upon glucose starvation PubMed

Expression and regulation

• Operon: yhaO-sbcE-yhaM PubMed

• Expression browser: yhaM PubMed

• Sigma factor:

• Regulation:
  • induced by DNA damage (LexA) PubMed
  • putatively regulated by CcpN PubMed

• Regulatory mechanism:
  • LexA: transcription repression PubMed

• Additional information: subject to Clp-dependent proteolysis upon glucose starvation PubMed
  • number of protein molecules per cell (minimal medium with glucose and ammonium): 292 PubMed
  • number of protein molecules per cell (complex medium with amino acids, without glucose): 948 PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

David Bechhofer, Mount Sinai School, New York, USA Homepage