Difference between revisions of "AccC"
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU24340&redirect=T BSU24340] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/accBC-yqhY.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/accBC-yqhY.html] | ||
| Line 103: | Line 104: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU24340&redirect=T BSU24340] | ||
* '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?structureId=1BNC 1BNC] (the protein from ''E. coli'') {{PubMed|7915138}} | * '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?structureId=1BNC 1BNC] (the protein from ''E. coli'') {{PubMed|7915138}} | ||
Revision as of 14:11, 2 April 2014
- Description: acetyl-CoA carboxylase (biotin carboxylase subunit)
| Gene name | accC |
| Synonyms | yqhX |
| Essential | yes PubMed |
| Product | acetyl-CoA carboxylase (biotin carboxylase subunit) |
| Function | production of malonyl-CoA, the substrate for fatty acid biosynthesis |
| Gene expression levels in SubtiExpress: accC | |
| Interactions involving this protein in SubtInteract: AccC | |
| Metabolic function and regulation of this protein in SubtiPathways: accC | |
| MW, pI | 49 kDa, 4.72 |
| Gene length, protein length | 1350 bp, 450 aa |
| Immediate neighbours | yqhY, accB |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
biosynthesis of lipids, essential genes
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU24340
Phenotypes of a mutant
essential PubMed
Database entries
- BsubCyc: BSU24340
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATP + biotin-carboxyl-carrier protein + CO2 = ADP + phosphate + carboxybiotin-carboxyl-carrier protein (according to Swiss-Prot)
- Protein family:
- Paralogous protein(s): YotE
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- BsubCyc: BSU24340
- UniProt: P49787
- KEGG entry: [3]
Additional information
Expression and regulation
- Sigma factor:
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Stephen W White, Jie Zheng, Yong-Mei Zhang, Rock
The structural biology of type II fatty acid biosynthesis.
Annu Rev Biochem: 2005, 74;791-831
[PubMed:15952903]
[WorldCat.org]
[DOI]
(P p)
Original Publications
