Difference between revisions of "PbpE"
| Line 40: | Line 40: | ||
{{SubtiWiki category|[[cell wall synthesis]]}}, | {{SubtiWiki category|[[cell wall synthesis]]}}, | ||
{{SubtiWiki category|[[cell wall degradation/ turnover]]}}, | {{SubtiWiki category|[[cell wall degradation/ turnover]]}}, | ||
| − | {{SubtiWiki category|[[cell envelope stress proteins (controlled by SigM, V, W, X, Y)]]}} | + | {{SubtiWiki category|[[cell envelope stress proteins (controlled by SigM, V, W, X, Y)]]}}, |
| + | [[most abundant proteins]] | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| Line 60: | Line 61: | ||
=== Additional information=== | === Additional information=== | ||
| − | |||
| − | |||
| − | |||
=The protein= | =The protein= | ||
| Line 78: | Line 76: | ||
* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' | + | * '''[[Domains]]:''' |
* '''Modification:''' | * '''Modification:''' | ||
| − | * ''' | + | * '''[[Cofactors]]:''' |
* '''Effectors of protein activity:''' | * '''Effectors of protein activity:''' | ||
| Line 115: | Line 113: | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | * '''Additional information:''' the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed] | + | * '''Additional information:''' |
| + | ** the mRNA is very stable (half-life > 15 min) [http://www.ncbi.nlm.nih.gov/sites/entrez/12884008 PubMed] | ||
| + | ** belongs to the 100 [[most abundant proteins]] {{PubMed|15378759}} | ||
=Biological materials = | =Biological materials = | ||
| Line 137: | Line 137: | ||
=References= | =References= | ||
| − | <pubmed>8491712,12533473,9987136,19063962,12884008,12207695,7592498, 20817675</pubmed> | + | <pubmed>8491712,12533473,9987136,19063962,12884008,12207695,7592498, 20817675 15378759</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:32, 5 March 2014
- Description: penicillin-binding protein PBP 4* (spore cortex)
| Gene name | pbpE |
| Synonyms | |
| Essential | no |
| Product | penicillin-binding protein PBP 4* (spore cortex) |
| Function | endopeptidase |
| Gene expression levels in SubtiExpress: pbpE | |
| MW, pI | 51 kDa, 4.835 |
| Gene length, protein length | 1353 bp, 451 aa |
| Immediate neighbours | racX, sacB |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
cell wall synthesis, cell wall degradation/ turnover, cell envelope stress proteins (controlled by SigM, V, W, X, Y), most abundant proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU34440
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: beta-lactamase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
- Localization: spore cortex
Database entries
- Structure: 3TG9 (from Bacillus halodurans, 27% identity, 59% similarity)
- UniProt: P32959
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
- the mRNA is very stable (half-life > 15 min) PubMed
- belongs to the 100 most abundant proteins PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
