Difference between revisions of "PhrI"

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=== Additional information===
 
=== Additional information===
 
 
 
  
 
=The protein=
 
=The protein=
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* '''Kinetic information:'''
 
* '''Kinetic information:'''
  
* '''Domains:'''  
+
* '''[[Domains]]:'''  
  
 
* '''Modification:'''
 
* '''Modification:'''
  
* '''Cofactor(s):'''
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* '''[[Cofactors]]:'''
  
 
* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=phrI_548438_548557_1 phrI] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=phrI_548438_548557_1 phrI] {{PubMed|22383849}}
  
* '''Sigma factor:'''  
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* '''[[Sigma factor]]:'''  
 
** ''phrI'': [[SigA]], [[SigH]] {{PubMed|11466295}}
 
** ''phrI'': [[SigA]], [[SigH]] {{PubMed|11466295}}
  

Revision as of 09:09, 19 February 2014

Gene name phrI
Synonyms
Essential no
Product phosphatase (RapI) regulator
Function control of the transfer of the
mobile genetic element ICEBs1
Gene expression levels in SubtiExpress: phrI
Interactions involving this protein in SubtInteract: PhrI
MW, pI 4 kDa, 8.907
Gene length, protein length 117 bp, 39 aa
Immediate neighbours rapI, yddM
Sequences Protein DNA DNA_with_flanks
Genetic context
PhrI context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PhrI expression.png















Categories containing this gene/protein

protein modification, transcription factors and their control, quorum sensing, mobile genetic elements, short peptides

This gene is a member of the following regulons

SigH regulon

The gene

Basic information

  • Locus tag: BSU05020

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: binds RapI and inhibits its activity, this results in contiuned repression of the genes for the transfer of the mobile genetic element ICEBs1 by ImmR PubMed
  • Protein family: phr family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Modification:
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Jennifer M Auchtung, Catherine A Lee, Katherine L Garrison, Alan D Grossman
Identification and characterization of the immunity repressor (ImmR) that controls the mobile genetic element ICEBs1 of Bacillus subtilis.
Mol Microbiol: 2007, 64(6);1515-28
[PubMed:17511812] [WorldCat.org] [DOI] (P p)

R S McQuade, N Comella, A D Grossman
Control of a family of phosphatase regulatory genes (phr) by the alternate sigma factor sigma-H of Bacillus subtilis.
J Bacteriol: 2001, 183(16);4905-9
[PubMed:11466295] [WorldCat.org] [DOI] (P p)