Difference between revisions of "TasA"
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* '''Mutant:''' | * '''Mutant:''' | ||
** 1S121 ( ''tasA''::''spec''), {{PubMed|10049401}}, available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S121&Search=1S121 BGSC] | ** 1S121 ( ''tasA''::''spec''), {{PubMed|10049401}}, available at [http://pasture.asc.ohio-state.edu/BGSC/getdetail.cfm?bgscid=1S121&Search=1S121 BGSC] | ||
+ | ** GP1571(cat), available in [[Stülke]] lab | ||
** GP1672 (''sinR-tasA''::''cat''), available in [[Stülke]] lab | ** GP1672 (''sinR-tasA''::''cat''), available in [[Stülke]] lab | ||
** GP1663 (''yghG-sinI-sinR-tasA''), available in [[Stülke]] lab | ** GP1663 (''yghG-sinI-sinR-tasA''), available in [[Stülke]] lab | ||
+ | |||
* '''Expression vector:''' | * '''Expression vector:''' |
Revision as of 08:56, 28 January 2014
- Description: major component of biofilm matrix, forms amyloid fibers
Gene name | tasA |
Synonyms | cotN, yqhF |
Essential | no |
Product | major component of biofilm matrix |
Function | biofilm formation |
Gene expression levels in SubtiExpress: tasA | |
Interactions involving this protein in SubtInteract: TasA | |
Regulation of this protein in SubtiPathways: tasA | |
MW, pI | 28 kDa, 5.442 |
Gene length, protein length | 783 bp, 261 aa |
Immediate neighbours | sinR, sipW |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
AbrB regulon, RemA regulon, SinR regulon
The gene
Basic information
- Locus tag: BSU24620
Phenotypes of a mutant
- altered cell death pattern in colonies PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: forms amyloid fibers that bind cells together in the biofilm PubMed
- Protein family: peptidase M73 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: P54507
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Adam Driks
Tapping into the biofilm: insights into assembly and disassembly of a novel amyloid fibre in Bacillus subtilis.
Mol Microbiol: 2011, 80(5);1133-6
[PubMed:21488983]
[WorldCat.org]
[DOI]
(I p)
Massimiliano Marvasi, Pieter T Visscher, Lilliam Casillas Martinez
Exopolymeric substances (EPS) from Bacillus subtilis: polymers and genes encoding their synthesis.
FEMS Microbiol Lett: 2010, 313(1);1-9
[PubMed:20735481]
[WorldCat.org]
[DOI]
(I p)
Yunrong Chai, Thomas Norman, Roberto Kolter, Richard Losick
An epigenetic switch governing daughter cell separation in Bacillus subtilis.
Genes Dev: 2010, 24(8);754-65
[PubMed:20351052]
[WorldCat.org]
[DOI]
(I p)
Original publications