YxaM

• Description: similar to antibiotic resistance protein
  
  

Gene name	yxaM
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: yxaM
Metabolic function and regulation of this protein in SubtiPathways: yxaM
MW, pI	44 kDa, 8.306
Gene length, protein length	1197 bp, 399 aa
Immediate neighbours	asnH, yxaL
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

resistance against toxins/ antibiotics, membrane proteins

This gene is a member of the following regulons

AbrB regulon, CodY regulon

The gene

Basic information

• Locus tag: BSU39930

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: major facilitator superfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization: cell membrane (according to Swiss-Prot)

Database entries

• Structure:

• UniProt: P42112

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yxbB-yxbA-yxnB-asnH-yxaM PubMed

• Expression browser: yxaM PubMed

• Sigma factor:

• Regulation:
  • repressed during growth in the presence of branched chain amino acids (CodY) PubMed
  • repressed during logrithmic growth (AbrB) PubMed

• Regulatory mechanism:
  • CodY: transcription repression PubMed
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: