Difference between revisions of "LevR"

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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=LevR LevR]
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://subtiwiki.uni-goettingen.de/interact/ ''Subt''Interact]''': [http://subtiwiki.uni-goettingen.de/interact/index.php?protein=LevR LevR]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/carbohydrate_metabolic_pathways.html Sugar catabolism]'''
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/subtipathways/search.php?enzyme=levR levR]'''
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 105 kDa, 5.943   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 105 kDa, 5.943   

Revision as of 11:19, 7 January 2014

Gene name levR
Synonyms
Essential no
Product transcriptional activator, PRD-type
(for SigL-dependent promoter)
Function regulation of levan and fructose utilization
Gene expression levels in SubtiExpress: levR
Interactions involving this protein in SubtInteract: LevR
Metabolic function and regulation of this protein in SubtiPathways:
levR
MW, pI 105 kDa, 5.943
Gene length, protein length 2814 bp, 938 aa
Immediate neighbours levD, aapA
Sequences Protein DNA DNA_with_flanks
Genetic context
LevR context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
LevR expression.png




























Categories containing this gene/protein

utilization of specific carbon sources, transcription factors and their control, phosphoproteins

This gene is a member of the following regulons

The LevR regulon:

The gene

Basic information

  • Locus tag: BSU27080

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: binding to the upstream activating sequence in front of the levD gene results in activation of transcription of the levD-levE-levF-levG-sacC operon, bining occurs in the presence of fructose
  • Protein family: transcriptional antiterminator bglG family (according to Swiss-Prot), Attention: this is wrong: LicR is a transcription activator, the similarity to the BglG family is limited to the PTS-regulation domains
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References