YydJ

• Description: ABC transporter (resistance), permease, export of YydF
  
  

Gene name	yydJ
Synonyms
Essential	no
Product	ABC transporter (resistance), permease
Function	control of LiaR-LiaS activity
Gene expression levels in SubtiExpress: yydJ
Interactions involving this protein in SubtInteract: YydJ
MW, pI	27 kDa, 9.469
Gene length, protein length	720 bp, 240 aa
Immediate neighbours	yyzN, yydI
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

ABC transporters, transcription factors and their control, membrane proteins

This gene is a member of the following regulons

AbrB regulon, Rok regulon

The gene

Basic information

• Locus tag: BSU40140

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:
  • YydI-(YydJ-YydH) PubMed

• Localization: cell membrane PubMed

Database entries

• Structure:

• UniProt: Q45592

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yydF-yydG-yydH-yydI-yydJ PubMed

• Expression browser: yydJ PubMed

• Sigma factor: SigA PubMed

• Regulation: activated after transition to stationary phase(AbrB) PubMed
  • repressed by Rok PubMed
  • strongly repressed in response to glucose starvation in M9 medium PubMed

• Regulatory mechanism:
  • AbrB: transcription repression PubMed
  • Rok: transcription repression PubMed

• Additional information:
  • the amount of the mRNA is substantially decreased upon depletion of RNase Y PubMed

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Reviews

Susanne Gebhard
ABC transporters of antimicrobial peptides in Firmicutes bacteria - phylogeny, function and regulation.
Mol Microbiol: 2012, 86(6);1295-317
[PubMed:23106164] [WorldCat.org] [DOI] (I p)