Difference between revisions of "PpsB"

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|style="background:#ABCDEF;" align="center"|'''Function''' || production of the antibacterial compound plipastatin  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || production of the antibacterial compound plipastatin  
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU18330 ppsB]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU18330 ppsB]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 289 kDa, 5.063   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 289 kDa, 5.063   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ppsC]]'', ''[[ppsA]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[ppsC]]'', ''[[ppsA]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB13716&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU18330 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU18330 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU18330 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:ppsB_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:ppsB_context.gif]]

Revision as of 12:57, 13 May 2013

  • Description: plipastatin synthetase

Gene name ppsB
Synonyms
Essential no
Product plipastatin synthetase
Function production of the antibacterial compound plipastatin
Gene expression levels in SubtiExpress: ppsB
MW, pI 289 kDa, 5.063
Gene length, protein length 7680 bp, 2560 aa
Immediate neighbours ppsC, ppsA
Sequences Protein DNA Advanced_DNA
Genetic context
PpsB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
PpsB expression.png
























Categories containing this gene/protein

miscellaneous metabolic pathways, biosynthesis of antibacterial compounds

This gene is a member of the following regulons

AbrB regulon

The gene

Basic information

  • Locus tag: BSU18330

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: ATP-dependent AMP-binding enzyme family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [2]
  • E.C. number:

Additional information

Expression and regulation

  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

K Tsuge, T Ano, M Hirai, Y Nakamura, M Shoda
The genes degQ, pps, and lpa-8 (sfp) are responsible for conversion of Bacillus subtilis 168 to plipastatin production.
Antimicrob Agents Chemother: 1999, 43(9);2183-92
[PubMed:10471562] [WorldCat.org] [DOI] (P p)

Valentina Tosato, Alessandra M Albertini, Michela Zotti, Sabrina Sonda, Carlo V Bruschi
Sequence completion, identification and definition of the fengycin operon in Bacillus subtilis 168.
Microbiology (Reading): 1997, 143 ( Pt 11);3443-3450
[PubMed:9387222] [WorldCat.org] [DOI] (P p)