RNA degradosome

Components of the RNA degradosome

• RNase Y: ssRNA endonuclease
• RNase J1: 5'-3' exonuclease, does also have endonuclease activity
• polynucleotide phosphorylase: 3'-5' exonuclease
• RNase J2: ssRNA endonuclease, may also have exonuclease activity
• CshA
• enolase
• phosphofructokinase

Related pages

• RNases
• DEAD-box RNA helicases

Reviews on the B. subtilis RNA degradosome

Lehnik-Habrink M, Lewis RJ, Mäder U, Stülke J    
RNA degradation in Bacillus subtilis: an interplay of
essential endo- and exoribonucleases. 
Mol Microbiol.: 2012, 84(6) 1005-1017. 
PubMed:22568516

Original publications on the B. subtilis RNA degradosome

Martin Lehnik-Habrink, Henrike Pförtner, Leonie Rempeters, Nico Pietack, Christina Herzberg, Jörg Stülke
The RNA degradosome in Bacillus subtilis: identification of CshA as the major RNA helicase in the multiprotein complex.
Mol Microbiol: 2010, 77(4);958-71
[PubMed:20572937] [WorldCat.org] [DOI] (I p)

Fabian M Commichau, Fabian M Rothe, Christina Herzberg, Eva Wagner, Daniel Hellwig, Martin Lehnik-Habrink, Elke Hammer, Uwe Völker, Jörg Stülke
Novel activities of glycolytic enzymes in Bacillus subtilis: interactions with essential proteins involved in mRNA processing.
Mol Cell Proteomics: 2009, 8(6);1350-60
[PubMed:19193632] [WorldCat.org] [DOI] (I p)

General reviews on the RNA degradosome

Additional reviews: PubMed