Difference between revisions of "BacD"

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=== Basic information/ Evolution ===
 
=== Basic information/ Evolution ===
  
* '''Catalyzed reaction/ biological activity:''' ATP + an L-amino acid + an L-amino acid = ADP + phosphate + L-aminoacyl-L-amino acid (according to Swiss-Prot)
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* '''Catalyzed reaction/ biological activity:'''  
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** ligation of anticapsin to L-Ala to form bacilysin, ultimate step in bacilysin biosynthesis {{PubMed|23317005}}
  
 
* '''Protein family:'''
 
* '''Protein family:'''
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=References=
 
=References=
'''Additional publications:''' {{PubMed|12697329,21709425,22298000}}
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'''Additional publications:''' {{PubMed|23317005,12697329,21709425,22298000}}
 
<pubmed>16030213,12372825,19352016,19801406 21948839 22407814 </pubmed>
 
<pubmed>16030213,12372825,19352016,19801406 21948839 22407814 </pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 18:34, 16 January 2013

  • Description: alanine-anticapsin ligase

Gene name bacD
Synonyms ywfE, ipa-83d
Essential no
Product alanine-anticapsin ligase
Function biosynthesis of the antibiotic bacilysin
Gene expression levels in SubtiExpress: bacD
MW, pI 52 kDa, 4.679
Gene length, protein length 1416 bp, 472 aa
Immediate neighbours bacE, bacC
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YwfE context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
BacD expression.png















Categories containing this gene/protein

miscellaneous metabolic pathways, biosynthesis of antibacterial compounds

This gene is a member of the following regulons

AbrB regulon, CodY regulon, ScoC regulon

The gene

Basic information

  • Locus tag: BSU37710

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
    • ligation of anticapsin to L-Ala to form bacilysin, ultimate step in bacilysin biosynthesis PubMed
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • KEGG entry: [2]

Additional information

Expression and regulation

  • Regulation:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed