RemB

• Description: involved in the activation of biofilm matrix biosynthetic operons, acts in parallel to SinR, AbrB, and DegU
  
  

Gene name	remB
Synonyms	yaaB
Essential	no
Product	regulator of the extracellular matrix
Function	regulation of biofilm formation
Gene expression levels in SubtiExpress: remB
MW, pI	5 kDa, 8.796
Gene length, protein length	156 bp, 52 aa
Immediate neighbours	recF, gyrB
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

biofilm formation

The gene

Basic information

• Locus tag: BSU00050

Phenotypes of a mutant

• • smooth colonies on MsGG medium, no biofilm formation PubMed

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P37525

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yaaA-recF-remB-gyrB PubMed

• Expression browser: remB PubMed

• Sigma factor: SigA PubMed

• Regulation:

• Regulatory mechanism:

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

Labs working on this gene/protein

Daniel Kearns, Indiana University, Bloomington, USA, homepage

References

Additional publications: PubMed

Jared T Winkelman, Kris M Blair, Daniel B Kearns
RemA (YlzA) and RemB (YaaB) regulate extracellular matrix operon expression and biofilm formation in Bacillus subtilis.
J Bacteriol: 2009, 191(12);3981-91
[PubMed:19363116] [WorldCat.org] [DOI] (I p)

N Ogasawara, S Moriya, H Yoshikawa
Structure and function of the region of the replication origin of the Bacillus subtilis chromosome. IV. Transcription of the oriC region and expression of DNA gyrase genes and other open reading frames.
Nucleic Acids Res: 1985, 13(7);2267-79
[PubMed:2987848] [WorldCat.org] [DOI] (P p)

Eric R Pozsgai, Kris M Blair, Daniel B Kearns
Modified mariner transposons for random inducible-expression insertions and transcriptional reporter fusion insertions in Bacillus subtilis.
Appl Environ Microbiol: 2012, 78(3);778-85
[PubMed:22113911] [WorldCat.org] [DOI] (I p)