Difference between revisions of "PutC"
m (Reverted edits by 134.76.70.252 (talk) to last revision by Jstuelk) |
|||
| Line 1: | Line 1: | ||
| − | + | * '''Description:''' 1-pyrroline-5-carboxylate dehydrogenase <br/><br/> | |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
| Line 13: | Line 13: | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || proline utilization | |style="background:#ABCDEF;" align="center"|'''Function''' || proline utilization | ||
| − | |||
| − | |||
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/glutamate.html Ammonium/ glutamate]''' | |colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/glutamate.html Ammonium/ glutamate]''' | ||
| Line 30: | Line 28: | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:ycgN_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:ycgN_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
| − | |||
| − | |||
|- | |- | ||
|} | |} | ||
__TOC__ | __TOC__ | ||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
| − | |||
<br/><br/><br/><br/><br/><br/> | <br/><br/><br/><br/><br/><br/> | ||
| Line 114: | Line 104: | ||
* '''Operon:''' ''[[putB]]-[[putC]]-[[putP]]'' {{PubMed|21840319,22139509}} | * '''Operon:''' ''[[putB]]-[[putC]]-[[putP]]'' {{PubMed|21840319,22139509}} | ||
| − | * | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|21840319,21964733,22139509}} |
| − | |||
| − | |||
* '''Regulation:''' | * '''Regulation:''' | ||
Revision as of 11:05, 7 August 2012
- Description: 1-pyrroline-5-carboxylate dehydrogenase
| Gene name | putC |
| Synonyms | ycgN |
| Essential | no |
| Product | 1-pyrroline-5-carboxylate dehydrogenase |
| Function | proline utilization |
| Metabolic function and regulation of this protein in SubtiPathways: Ammonium/ glutamate | |
| MW, pI | 56 kDa, 5.372 |
| Gene length, protein length | 1545 bp, 515 aa |
| Immediate neighbours | putB, putP |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
CodY regulon, PutR regulon, Spo0A regulon
The gene
Basic information
- Locus tag: BSU03210
Phenotypes of a mutant
- no growth with proline as single source of carbon or nitrogen PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: (S)-1-pyrroline-5-carboxylate + NAD(P)+ + 2 H2O = L-glutamate + NAD(P)H (according to Swiss-Prot)
- Protein family: RocA subfamily (according to Swiss-Prot)
- Paralogous protein(s): RocA, additional similar proteins: YfmT, AldY, YcbD, GabD, GbsA, DhaS, IolA, AldX, YwdH
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 3RJL (1-pyrroline-5-carboxylate dehydrogenase from Bacillus licheniformis, 90% identity, 97% similarity)
- UniProt: P94391
- KEGG entry: [3]
- E.C. number: 1.5.1.12
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications:PubMed
