Difference between revisions of "NtdC"

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|colspan="2" | '''Genetic context''' <br/> [[Image:yhjJ_context.gif]]
 
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|colspan="2" |'''[http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ntdC_1126400_1127452_-1 Expression at a glance]'''&#160;&#160;&#160;{{PubMed|22383849}}<br/>[[Image:ntdC_expression.png|500px]]
 
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Revision as of 17:06, 18 April 2012

  • Description: synthesis of the antibiotic neotrehalosadiamine

Gene name ntdC
Synonyms yhjJ
Essential no
Product unknown
Function synthesis of the antibiotic neotrehalosadiamine
MW, pI 39 kDa, 6.227
Gene length, protein length 1050 bp, 350 aa
Immediate neighbours glcP, ntdB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YhjJ context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
NtdC expression.png
























Categories containing this gene/protein

miscellaneous metabolic pathways, biosynthesis of antibacterial compounds

This gene is a member of the following regulons

NtdR regulon

The gene

Basic information

  • Locus tag: BSU10530

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: gfo/idh/mocA family (according to Swiss-Prot)

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: induced by 3,3'-neotrehalosadiamine (NtdR) PubMed
  • Regulatory mechanism: NtdR: positive regulator PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Reviews

Takashi Inaoka, Kozo Ochi
Activation of dormant secondary metabolism neotrehalosadiamine synthesis by an RNA polymerase mutation in Bacillus subtilis.
Biosci Biotechnol Biochem: 2011, 75(4);618-23
[PubMed:21512256] [WorldCat.org] [DOI] (I p)

Original publications