iolU

iolU
168

minor NADP-dependent scyllo-inositol dehydrogenase

Locus
BSU_31170
Molecular weight
36.36 kDa
Isoelectric point
5.15
Protein length
328 aaSequenceBlast
Gene length
987 bpSequenceBlast
Function
utilization of scyllo-inosose
Product
minor NADP-dependent scyllo-inositol dehydrogenase
Essential
no
Synonyms
iolU, yulF
Outlinks
BsubCyc SubtiList UniProt STRING Genoscapist PaperBLAST

Genomic Context

Categories containing this gene/protein

List of homologs in different organisms, belongs to COG0673 (Galperin et al., 2021)

This gene is a member of the following regulons

Gene
Coordinates
3,196,906  3,197,892
The protein
Catalyzed reaction/ biological activity
NADPH-dependent conversion of scyllo-inosose to scyllo-inositol PubMed
NADP+ + scyllo-inositol --> H+ + NADPH + scyllo-inosose (according to UniProt)
Protein family
Gfo/Idh/MocA family (according to UniProt)
Cofactors
NADP+ PubMed
Structure
4NHE (PDB) (oxidoreductase from Streptococcus pneumoniae)
O05265 (AlphaFold)
Paralogous protein(s)
IolG, YrbE, IolX, YfiI, NtdC, YteT, IolW
Expression and Regulation
Operons
Genes
iolU
Description
PubMed
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iolU

2025-03-09 12:51:14

ghost

58

48e31013e46b4b34dd8f1906ffc2883897961607

DEBF2C42B05AC261A3FE97A7D99CE62441D01F9D

Biological materials
Mutant
MGNA-A228 (yulF::erm), available at the NBRP B. subtilis, Japan
BKE31170 (iolU::erm  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACTCGTATCGCTCCTTTTG,  downstream forward: _UP4_TAAAAAAATCCGCCCGCGTG
BKK31170 (iolU::kan  trpC2) available at BGSC,  PubMed, upstream reverse: _UP1_CACTCGTATCGCTCCTTTTG,  downstream forward: _UP4_TAAAAAAATCCGCCCGCGTG
References
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Page visits: 2638

Time of last update: 2025-03-31 15:15:21

Author of last update: Melvin.boenninger