Difference between revisions of "GbsA"
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|style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1470 bp, 490 aa | |style="background:#ABCDEF;" align="center"| '''Gene length, protein length''' || 1470 bp, 490 aa | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[gbsB]]'', ''[[ | + | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[gbsB]]'', ''[[gbsR]]'' |
|- | |- | ||
|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB15084]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | |colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+[EMBLCDS:CAB15084]+-newId sequences] <br/> (Barbe ''et al.'', 2009)''' | ||
| Line 104: | Line 104: | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| − | ** induced by choline ([[ | + | ** induced by choline ([[GbsR]]) {{PubMed|22408163,8752328}} |
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| − | ** [[ | + | ** [[GbsR]]: transcription repression {{PubMed|22408163}} |
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 132: | Line 132: | ||
=References= | =References= | ||
| − | + | '''Additional publications:''' {{PubMed|22408163}} | |
<pubmed>9297465,8752328, 21296969 </pubmed> | <pubmed>9297465,8752328, 21296969 </pubmed> | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 08:29, 15 March 2012
- Description: glycine betaine-aldehyde dehydrogenase, glycine betaine synthesis
| Gene name | gbsA |
| Synonyms | |
| Essential | no |
| Product | glycine betaine-aldehyde dehydrogenase |
| Function | osmoprotection |
| Metabolic function and regulation of this protein in SubtiPathways: Stress | |
| MW, pI | 53 kDa, 4.713 |
| Gene length, protein length | 1470 bp, 490 aa |
| Immediate neighbours | gbsB, gbsR |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, coping with hyper-osmotic stress
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU31060
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Betaine aldehyde + NAD+ + H2O = betaine + NADH (according to Swiss-Prot)
- Protein family: aldehyde dehydrogenase family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 3RHH (from from Bacillus halodurans C-125 complexed with NADP, 31% identity, 67% similarity)
- UniProt: P71016
- KEGG entry: [2]
- E.C. number: 1.2.1.8
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Erhard Bremer, University of Marburg, Germany homepage
Your additional remarks
References
Additional publications: PubMed
