Difference between revisions of "TapA"
| Line 1: | Line 1: | ||
| − | * '''Description:''' required for the | + | * '''Description:''' required for the anchoring of the [[TasA]] amyloid fibers to the cell and for the initiation of fiber polymerization, minor fiber component |
| + | <br/><br/> | ||
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Gene name''' | |style="background:#ABCDEF;" align="center"|'''Gene name''' | ||
| − | |'' | + | |''tapA'' |
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yqhD '' | + | |style="background:#ABCDEF;" align="center"| '''Synonyms''' || ''yqhD, yqxM '' |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
|- | |- | ||
| − | |style="background:#ABCDEF;" align="center"| '''Product''' || | + | |style="background:#ABCDEF;" align="center"| '''Product''' || [[TasA]] anchoring/assembly protein |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || [[biofilm formation]] | |style="background:#ABCDEF;" align="center"|'''Function''' || [[biofilm formation]] | ||
| Line 81: | Line 82: | ||
* '''Cofactor(s):''' | * '''Cofactor(s):''' | ||
| − | * '''Effectors of protein activity:''' | + | * '''Effectors of protein activity:''' D-amino acids lead to disappearance of TapA from the cell wall {{PubMed|21477127}} |
| − | * '''Interactions:''' | + | * '''Interactions:''' [[TapA]]-[[TasA]] {{PubMed|21477127}} |
| − | * '''Localization:''' cell | + | * '''Localization:''' attached to the cell surface (on the outside of the cell), associated with peptidoglycan {{PubMed|21477127}} |
=== Database entries === | === Database entries === | ||
| Line 101: | Line 102: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' ''[[ | + | * '''Operon:''' ''[[tapA]]-[[sipW]]-[[tasA]]'' [http://www.ncbi.nlm.nih.gov/sites/entrez/16430695 PubMed] |
* '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/16430695 PubMed] | * '''[[Sigma factor]]:''' [[SigA]] [http://www.ncbi.nlm.nih.gov/sites/entrez/16430695 PubMed] | ||
| Line 136: | Line 137: | ||
=References= | =References= | ||
| − | <pubmed>18430133,18047568,18647168, 20351052,16430695,10464223,17720793, 19605685 20431016 10559173 </pubmed> | + | <pubmed>18430133,18047568,18647168, 20351052,16430695,10464223,17720793, 19605685 20431016 10559173 21477127 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 08:22, 12 April 2011
- Description: required for the anchoring of the TasA amyloid fibers to the cell and for the initiation of fiber polymerization, minor fiber component
| Gene name | tapA |
| Synonyms | yqhD, yqxM |
| Essential | no |
| Product | TasA anchoring/assembly protein |
| Function | biofilm formation |
| Regulation of this protein in SubtiPathways: Biofilm, Protein secretion | |
| MW, pI | 28 kDa, 6.677 |
| Gene length, protein length | 759 bp, 253 aa |
| Immediate neighbours | sipW, yqzG |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
biofilm formation, membrane proteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU24640
Phenotypes of a mutant
The mutants are able to form a biofilm in the presence of D-amino acids PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: D-amino acids lead to disappearance of TapA from the cell wall PubMed
- Localization: attached to the cell surface (on the outside of the cell), associated with peptidoglycan PubMed
Database entries
- Structure:
- UniProt: P40949
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
