Difference between revisions of "BdhA"
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* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[AbrB]]: transcription repression {{PubMed|20817675}} | ||
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=References= | =References= | ||
| − | <pubmed>18820069,, </pubmed> | + | <pubmed>18820069,20817675, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 13:38, 13 September 2010
- Description: acetoine/ butanediol dehydrogenase
| Gene name | bdhA |
| Synonyms | ydjL |
| Essential | no |
| Product | acetoine/ butanediol dehydrogenase |
| Function | overflow metabolism, fermentation |
| MW, pI | 37 kDa, 4.805 |
| Gene length, protein length | 1038 bp, 346 aa |
| Immediate neighbours | iolT, ydjM |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU06240
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: formation of butanediol from acetoin PubMed
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: O34788
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: bdhA (according to DBTBS)
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Onuma Chumsakul, Hiroki Takahashi, Taku Oshima, Takahiro Hishimoto, Shigehiko Kanaya, Naotake Ogasawara, Shu Ishikawa
Genome-wide binding profiles of the Bacillus subtilis transition state regulator AbrB and its homolog Abh reveals their interactive role in transcriptional regulation.
Nucleic Acids Res: 2011, 39(2);414-28
[PubMed:20817675]
[WorldCat.org]
[DOI]
(I p)
Wayne L Nicholson
The Bacillus subtilis ydjL (bdhA) gene encodes acetoin reductase/2,3-butanediol dehydrogenase.
Appl Environ Microbiol: 2008, 74(22);6832-8
[PubMed:18820069]
[WorldCat.org]
[DOI]
(I p)
