Difference between revisions of "YydH"

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* '''Description:''' membrane embedded protease M50 family member <br/><br/>
+
* '''Description:''' similar to [[ABC transporter]] (membrane protein)<br/><br/>
  
 
{| align="right" border="1" cellpadding="2"  
 
{| align="right" border="1" cellpadding="2"  
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|style="background:#ABCDEF;" align="center"| '''Essential''' || no  
 
|-
 
|-
|style="background:#ABCDEF;" align="center"| '''Product''' || protease
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|style="background:#ABCDEF;" align="center"| '''Product''' || [[ABC transporter]] (membrane protein)
 
|-
 
|-
|style="background:#ABCDEF;" align="center"|'''Function''' || control of LiaRS activity
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of [[LiaR]]-[[LiaS]] activity
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 29 kDa, 9.641   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 29 kDa, 9.641   
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* '''Effectors of protein activity:'''
 
* '''Effectors of protein activity:'''
  
* '''Interactions:'''
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* '''Interactions:''' [[YydI]]-([[YydJ]]-[[YydH]]) {{PubMed|10092453}}
  
* '''Localization:'''
+
* '''Localization:''' cell membrane {{PubMed|10092453}}
  
 
=== Database entries ===
 
=== Database entries ===

Revision as of 21:00, 14 January 2010

Gene name yydH
Synonyms
Essential no
Product ABC transporter (membrane protein)
Function control of LiaR-LiaS activity
MW, pI 29 kDa, 9.641
Gene length, protein length 756 bp, 252 aa
Immediate neighbours yydI, yydG
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YydH context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU40160

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization: cell membrane PubMed

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: activated after transition to stationary phase(AbrB) PubMed
  • Regulatory mechanism: AbrB: transcription repression PubMed
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Bronwyn G Butcher, Yi-Pin Lin, John D Helmann
The yydFGHIJ operon of Bacillus subtilis encodes a peptide that induces the LiaRS two-component system.
J Bacteriol: 2007, 189(23);8616-25
[PubMed:17921301] [WorldCat.org] [DOI] (I p)

Mark Albano, Wiep Klaas Smits, Linh T Y Ho, Barbara Kraigher, Ines Mandic-Mulec, Oscar P Kuipers, David Dubnau
The Rok protein of Bacillus subtilis represses genes for cell surface and extracellular functions.
J Bacteriol: 2005, 187(6);2010-9
[PubMed:15743949] [WorldCat.org] [DOI] (P p)

Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453] [WorldCat.org] [DOI] (P p)