Difference between revisions of "AccB"
| Line 78: | Line 78: | ||
=== Database entries === | === Database entries === | ||
| − | * '''Structure:''' | + | * '''Structure:''' [http://www.rcsb.org/pdb/explore/explore.do?structureId=1BDO 1BDO] (the protein from ''E. coli'') {{PubMed|8747466}} |
* '''UniProt:''' [http://www.uniprot.org/uniprot/P49786 P49786] | * '''UniProt:''' [http://www.uniprot.org/uniprot/P49786 P49786] | ||
| Line 124: | Line 124: | ||
<pubmed> 15952903 </pubmed> | <pubmed> 15952903 </pubmed> | ||
==Original Publications== | ==Original Publications== | ||
| − | <pubmed>7592499,, </pubmed> | + | <pubmed>7592499, 8747466, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 17:52, 6 January 2010
- Description: acetyl-CoA carboxylase (biotin carboxyl carrier subunit)
| Gene name | accB |
| Synonyms | fabE, yqhW |
| Essential | yes PubMed |
| Product | acetyl-CoA carboxylase (biotin carboxyl carrier subunit) |
| Function | production of malonyl-CoA, the substrate for fatty acid biosynthesis |
| MW, pI | 17 kDa, 4.394 |
| Gene length, protein length | 477 bp, 159 aa |
| Immediate neighbours | accC, spoIIIAH |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU24350
Phenotypes of a mutant
essential PubMed
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- UniProt: P49786
- KEGG entry: [3]
- E.C. number: 6.4.1.2
Additional information
AccB binds to StrepTactin, and may be co-purified when purifying Strep-tagged proteins by SPINE.
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Stephen W White, Jie Zheng, Yong-Mei Zhang, Rock
The structural biology of type II fatty acid biosynthesis.
Annu Rev Biochem: 2005, 74;791-831
[PubMed:15952903]
[WorldCat.org]
[DOI]
(P p)
Original Publications
