Difference between revisions of "FlgM"
| Line 87: | Line 87: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | |||
* '''Operon:''' | * '''Operon:''' | ||
| + | ** ''[[comFA]]-[[comFB]]-[[comFC]]-[[yvyF]]-[[flgM]]-[[yvyG]]-[[flgK]]-[[flgL]]'' {{PubMed|8412657}} | ||
| + | ** ''[[yvyF]]-[[flgM]]-[[yvyG]]-[[flgK]]-[[flgL]]'' {{PubMed|8045879}} | ||
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
| + | ** ''[[comFA]]'': [[SigA]] {{PubMed|8412657}} | ||
| + | ** ''[[yvyF]]'': [[SigD]] {{PubMed|8045879}} | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| + | |||
| + | * '''Regulatory mechanism:''' | ||
| + | ** [[ComK]]: transcription activation {{PubMed|8412657}} | ||
** [[ScoC]]: transcription repression {{PubMed|19898538}} | ** [[ScoC]]: transcription repression {{PubMed|19898538}} | ||
| Line 119: | Line 125: | ||
=References= | =References= | ||
| − | <pubmed>8955328,19898538 , </pubmed> | + | <pubmed>8955328,19898538 8412657 8045879 , </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 21:42, 30 December 2009
- Description: anti-SigD, regulation of flagellin, motility, and chemotaxis
| Gene name | flgM |
| Synonyms | |
| Essential | no |
| Product | anti-SigD |
| Function | control of SigD activity |
| MW, pI | 9 kDa, 9.918 |
| Gene length, protein length | 264 bp, 88 aa |
| Immediate neighbours | yvyG, yvyF |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU35430
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: flgM family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization:
Database entries
- Structure:
- UniProt: P39809
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Prashant Kodgire, K Krishnamurthy Rao
A dual mode of regulation of flgM by ScoC in Bacillus subtilis.
Can J Microbiol: 2009, 55(8);983-9
[PubMed:19898538]
[WorldCat.org]
[DOI]
(I p)
K Fredrick, J D Helmann
FlgM is a primary regulator of sigmaD activity, and its absence restores motility to a sinR mutant.
J Bacteriol: 1996, 178(23);7010-3
[PubMed:8955328]
[WorldCat.org]
[DOI]
(P p)
D B Mirel, P Lauer, M J Chamberlin
Identification of flagellar synthesis regulatory and structural genes in a sigma D-dependent operon of Bacillus subtilis.
J Bacteriol: 1994, 176(15);4492-500
[PubMed:8045879]
[WorldCat.org]
[DOI]
(P p)
J A Londoño-Vallejo, D Dubnau
comF, a Bacillus subtilis late competence locus, encodes a protein similar to ATP-dependent RNA/DNA helicases.
Mol Microbiol: 1993, 9(1);119-31
[PubMed:8412657]
[WorldCat.org]
[DOI]
(P p)
