Difference between revisions of "FtsX"
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| − | * '''Description:''' ABC transporter ( | + | * '''Description:''' ABC transporter ([[FtsE]]-[[FtsX]]), required for proper activation of [[Spo0A]] and initiation of sporulation <br/><br/> |
{| align="right" border="1" cellpadding="2" | {| align="right" border="1" cellpadding="2" | ||
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || ABC transporter ( | + | |style="background:#ABCDEF;" align="center"| '''Product''' || ABC transporter ([[FtsE]]-[[FtsX]]) |
|- | |- | ||
|style="background:#ABCDEF;" align="center"|'''Function''' || initiation of sporulation | |style="background:#ABCDEF;" align="center"|'''Function''' || initiation of sporulation | ||
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=Expression and regulation= | =Expression and regulation= | ||
| − | + | * '''Operon:''' ''[[ftsE]]-[[ftsX]]'' (according to [http://dbtbs.hgc.jp/COG/prom/ftsEX.html DBTBS]) | |
| − | * '''Operon:''' | ||
* '''[[Sigma factor]]:''' | * '''[[Sigma factor]]:''' | ||
Revision as of 21:11, 30 December 2009
- Description: ABC transporter (FtsE-FtsX), required for proper activation of Spo0A and initiation of sporulation
| Gene name | ftsX |
| Synonyms | |
| Essential | no |
| Product | ABC transporter (FtsE-FtsX) |
| Function | initiation of sporulation |
| MW, pI | 32 kDa, 10.016 |
| Gene length, protein length | 888 bp, 296 aa |
| Immediate neighbours | ctpB, ftsE |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU35250
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: FtsX subfamily (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cell membrane (according to Swiss-Prot), membrane associated PubMed
Database entries
- Structure:
- UniProt: O34876
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Hannes Hahne, Susanne Wolff, Michael Hecker, Dörte Becher
From complementarity to comprehensiveness--targeting the membrane proteome of growing Bacillus subtilis by divergent approaches.
Proteomics: 2008, 8(19);4123-36
[PubMed:18763711]
[WorldCat.org]
[DOI]
(I p)
Sharon Garti-Levi, Ronen Hazan, James Kain, Masaya Fujita, Sigal Ben-Yehuda
The FtsEX ABC transporter directs cellular differentiation in Bacillus subtilis.
Mol Microbiol: 2008, 69(4);1018-28
[PubMed:18573177]
[WorldCat.org]
[DOI]
(I p)
Virginie Molle, Masaya Fujita, Shane T Jensen, Patrick Eichenberger, José E González-Pastor, Jun S Liu, Richard Losick
The Spo0A regulon of Bacillus subtilis.
Mol Microbiol: 2003, 50(5);1683-701
[PubMed:14651647]
[WorldCat.org]
[DOI]
(P p)
Y Quentin, G Fichant, F Denizot
Inventory, assembly and analysis of Bacillus subtilis ABC transport systems.
J Mol Biol: 1999, 287(3);467-84
[PubMed:10092453]
[WorldCat.org]
[DOI]
(P p)
