Difference between revisions of "PbpE"

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=Expression and regulation=
 
=Expression and regulation=
 +
* '''Operon:''' ''[[pbpE]]-[[racX]]'' {{PubMed|8491712}}
  
* '''Operon:'''
+
* '''[[Sigma factor]]:''' [[SigW]] {{PubMed|8491712,12207695}}
 
 
* '''[[Sigma factor]]:''' [[SigA]], [[SigW]] [http://www.ncbi.nlm.nih.gov/sites/entrez/15758244 PubMed]
 
  
 
* '''Regulation:'''  
 
* '''Regulation:'''  
 
** repressed during logrithmic growth ([[AbrB]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/7592498 PubMed]
 
** repressed during logrithmic growth ([[AbrB]]) [http://www.ncbi.nlm.nih.gov/sites/entrez/7592498 PubMed]
 +
** induced by cell wall stress ([[SigW]]) {{PubMed|8491712,12207695}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
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=References=
 
=References=
  
<pubmed>8491712,12533473,9987136,19063962,12884008,,7592498, </pubmed>
+
<pubmed>8491712,12533473,9987136,19063962,12884008,12207695,7592498, </pubmed>
  
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 10:56, 30 December 2009

Gene name pbpE
Synonyms
Essential no
Product penicillin-binding protein PBP 4* (spore cortex)
Function endopeptidase
MW, pI 51 kDa, 4.835
Gene length, protein length 1353 bp, 451 aa
Immediate neighbours racX, sacB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
PbpE context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU34440

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: beta-lactamase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization: cell membrane (according to Swiss-Prot)

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information: the mRNA is very stable (half-life > 15 min) PubMed

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References