Difference between revisions of "RibR"
| Line 87: | Line 87: | ||
=Expression and regulation= | =Expression and regulation= | ||
| + | * '''Operon:''' ''[[ytmI]]-[[tcyJ]]-[[tcyK]]-[[tcyL]]-[[tcyM]]-[[tcyN]]-[[ytmO]]-[[ytnI]]-[[ytnJ]]-[[ribR]]-[[ytnL]]-[[ytnM]]'' {{PubMed|15668000}} | ||
| − | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|15272571}} | |
| − | |||
| − | * '''[[Sigma factor]]:''' [[SigA]] | ||
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** repressed in the presence of cysteine ([[CymR]]) {{PubMed|16109943}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[CymR]]: transcription repression {{PubMed|16109943}} | ||
| + | ** [[YtlI]]: transcription activation {{PubMed|16109943}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 117: | Line 119: | ||
=References= | =References= | ||
| − | <pubmed>17590224, 15668000 | + | <pubmed>17590224, 15668000 15272571 16109943</pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 22:24, 18 December 2009
- Description: cryptic riboflavin kinase, binds leader (RFN) rib operon mRNA, may have a regulatory role
| Gene name | ribR |
| Synonyms | ytnK |
| Essential | no |
| Product | cryptic riboflavin kinase |
| Function | regulation of rib operon expression |
| MW, pI | 26 kDa, 9.278 |
| Gene length, protein length | 690 bp, 230 aa |
| Immediate neighbours | ytnL, ytnJ |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU29300
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P94465
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Yuhei Higashitsuji, Annemarie Angerer, Sabine Berghaus, Birgit Hobl, Matthias Mack
RibR, a possible regulator of the Bacillus subtilis riboflavin biosynthetic operon, in vivo interacts with the 5'-untranslated leader of rib mRNA.
FEMS Microbiol Lett: 2007, 274(1);48-54
[PubMed:17590224]
[WorldCat.org]
[DOI]
(P p)
Pierre Burguière, Juliette Fert, Isabelle Guillouard, Sandrine Auger, Antoine Danchin, Isabelle Martin-Verstraete
Regulation of the Bacillus subtilis ytmI operon, involved in sulfur metabolism.
J Bacteriol: 2005, 187(17);6019-30
[PubMed:16109943]
[WorldCat.org]
[DOI]
(P p)
Irina M Solovieva, Rimma A Kreneva, Lubov Errais Lopes, Daniel A Perumov
The riboflavin kinase encoding gene ribR of Bacillus subtilis is a part of a 10 kb operon, which is negatively regulated by the yrzC gene product.
FEMS Microbiol Lett: 2005, 243(1);51-8
[PubMed:15668000]
[WorldCat.org]
[DOI]
(P p)
I M Solov'eva, R A Kreneva, L L Erraĭs, A S Mironov, D A Perumov
[Study of the mechanism for regulating ribR gene activity in Bacillus subtilis]. [Issledovanie mekhanizma reguliatsii aktivnosti gena ribR u Bacillus subtilis.]
Genetika: 2004, 40(5);716-20
[PubMed:15272571]
[WorldCat.org]
(P p)
