Difference between revisions of "Response regulator aspartate phosphatases"
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* [[RapD]]: [[RapD]] inhibits the DNA-binding activity of [[ComA]]-P | * [[RapD]]: [[RapD]] inhibits the DNA-binding activity of [[ComA]]-P | ||
* [[RapE]], [[PhrE]]: [[RapE]] dephosphorylates [[Spo0F]]-P | * [[RapE]], [[PhrE]]: [[RapE]] dephosphorylates [[Spo0F]]-P | ||
+ | * [[RapF]], [[PhrF]]: [[RapF]] inhibits the DNA-binding activity of [[ComA]]-P | ||
+ | * [[RapG]], [[PhrG]]: [[RapG]] inhibits the DNA-binding activity of [[DegU]]-P | ||
+ | * [[RapH]]: bifuntional protein: dephosphorylates [[Spo0F]]-P and inhibits the DNA-binding activity of [[ComA]]-P | ||
+ | * [[RapI]], [[PhrI]]: [[RapI]] inhibits the DNA-binding activity of [[ImmR]] | ||
+ | * [[RapJ]]: unknown function | ||
+ | * [[RapK]], [[PhrK]]: [[RapK]] inhibits the DNA-binding activity of [[ComA]]-P | ||
==Related lists== | ==Related lists== | ||
* [[two-component systems]] | * [[two-component systems]] | ||
* [[phosphorelay]] | * [[phosphorelay]] | ||
+ | |||
+ | ==Reviews== | ||
+ | <pubmed>8730857 11587783 </pubmed> |
Revision as of 20:38, 29 November 2009
These proteins contain the so-called tetratricopeptide repeats (TPRs) protein-protein interaction module. They control the phosphorelay for sporulation initiation by dephosphorylating Spo0F-P or they inhibit transcription factors by protein-protein interaction (without affecting phosphorylation). The activity of these proteins can be controlled by small peptides that are expressed as precursors, exported, and re-imported into the cell.
The RAP proteins of B. subtilis, their cognate peptides and target proteins
- RapA, PhrA: RapA dephosphorylates Spo0F-P
- RapB: dephosphorylates Spo0F-P
- RapC, PhrC: RapC inhibits the DNA-binding activity of ComA-P
- RapD: RapD inhibits the DNA-binding activity of ComA-P
- RapE, PhrE: RapE dephosphorylates Spo0F-P
- RapF, PhrF: RapF inhibits the DNA-binding activity of ComA-P
- RapG, PhrG: RapG inhibits the DNA-binding activity of DegU-P
- RapH: bifuntional protein: dephosphorylates Spo0F-P and inhibits the DNA-binding activity of ComA-P
- RapI, PhrI: RapI inhibits the DNA-binding activity of ImmR
- RapJ: unknown function
- RapK, PhrK: RapK inhibits the DNA-binding activity of ComA-P
Related lists
Reviews
M Perego, J A Brannigan
Pentapeptide regulation of aspartyl-phosphate phosphatases.
Peptides: 2001, 22(10);1541-7
[PubMed:11587783]
[WorldCat.org]
[DOI]
(P p)
M Perego, P Glaser, J A Hoch
Aspartyl-phosphate phosphatases deactivate the response regulator components of the sporulation signal transduction system in Bacillus subtilis.
Mol Microbiol: 1996, 19(6);1151-7
[PubMed:8730857]
[WorldCat.org]
[DOI]
(P p)