Difference between revisions of "RapI"
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| − | * '''Description:''' response regulator aspartate phosphatase, antagonist of [[ImmR]] <br/><br/> | + | * '''Description:''' [[response regulator aspartate phosphatase]], antagonist of [[ImmR]] <br/><br/> |
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|style="background:#ABCDEF;" align="center"| '''Essential''' || no | |style="background:#ABCDEF;" align="center"| '''Essential''' || no | ||
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| − | |style="background:#ABCDEF;" align="center"| '''Product''' || response regulator aspartate phosphatase | + | |style="background:#ABCDEF;" align="center"| '''Product''' || [[response regulator aspartate phosphatase]] |
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|style="background:#ABCDEF;" align="center"|'''Function''' || control of transfer of the mobile <br/>genetic element ICEBs1 | |style="background:#ABCDEF;" align="center"|'''Function''' || control of transfer of the mobile <br/>genetic element ICEBs1 | ||
Revision as of 20:15, 29 November 2009
- Description: response regulator aspartate phosphatase, antagonist of ImmR
| Gene name | rapI |
| Synonyms | yddL |
| Essential | no |
| Product | response regulator aspartate phosphatase |
| Function | control of transfer of the mobile genetic element ICEBs1 |
| MW, pI | 46 kDa, 5.054 |
| Gene length, protein length | 1173 bp, 391 aa |
| Immediate neighbours | yddK, phrI |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU05010
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: binds ImmR and inhibits its activity, this results in induction of the genes for the transfer of the mobile genetic element ICEBs1 PubMed
- Protein family: RAP family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity: binding of PhrI indicates that neighbour cells do already contain the genetic element ICEBs1, this results in inactivation of RapI PubMed
- Localization:
Database entries
- Structure:
- UniProt: P96649
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Jennifer M Auchtung, Catherine A Lee, Katherine L Garrison, Alan D Grossman
Identification and characterization of the immunity repressor (ImmR) that controls the mobile genetic element ICEBs1 of Bacillus subtilis.
Mol Microbiol: 2007, 64(6);1515-28
[PubMed:17511812]
[WorldCat.org]
[DOI]
(P p)
R S McQuade, N Comella, A D Grossman
Control of a family of phosphatase regulatory genes (phr) by the alternate sigma factor sigma-H of Bacillus subtilis.
J Bacteriol: 2001, 183(16);4905-9
[PubMed:11466295]
[WorldCat.org]
[DOI]
(P p)
