Difference between revisions of "SplB"

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(Expression and regulation)
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* '''[[Sigma factor]]:''' [[SigG]] {{PubMed|15699190,8021181}}
 
* '''[[Sigma factor]]:''' [[SigG]] {{PubMed|15699190,8021181}}
  
* '''Regulation:'''  
+
* '''Regulation:''' expressed during sporulation in the forespore ([[SigG]]) {{PubMed|16497325}}
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
** negative autoregulation by [[SplA]] {{PubMed|8021181}
+
** negative autoregulation by [[SplA]] {{PubMed|8021181}}
  
 
* '''Additional information:'''  
 
* '''Additional information:'''  

Revision as of 20:08, 31 October 2009

  • Description: spore photoproduct lyase

Gene name splB
Synonyms spl
Essential no
Product spore photoproduct lyase
Function protection of spore DNA against photodamage
MW, pI 39 kDa, 8.524
Gene length, protein length 1026 bp, 342 aa
Immediate neighbours splA, ykwB
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
SplB context.gif
This image was kindly provided by SubtiList



The gene

Basic information

  • Locus tag: BSU13930

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: 5-thyminyl-5,6-dihydrothymine (in DNA) = 2 thymine residues (in DNA) (according to Swiss-Prot)
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Interactions:
  • Localization:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation: expressed during sporulation in the forespore (SigG) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References