Difference between revisions of "TreA"
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=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' ''[[treP]]-[[treA]]-[[treR]]'' | + | * '''Operon:''' ''[[treP]]-[[treA]]-[[treR]]'' {{PubMed|8755887}} |
| − | * '''[[Sigma factor]]:''' [[SigA]] | + | * '''[[Sigma factor]]:''' [[SigA]] {{PubMed|8755887}} |
| − | * '''Regulation:''' repressed by glucose ([[CcpA]]) | + | * '''Regulation:''' |
| + | ** induced by trehalose ([[TreR]]) {{PubMed|8755887}} | ||
| + | ** repressed by glucose ([[CcpA]]) | ||
| − | * '''Regulatory mechanism:''' [[CcpA]]: transcription repression | + | * '''Regulatory mechanism:''' |
| + | ** [[TreR]]: transcription repression {{PubMed|8755887}} | ||
| + | ** [[CcpA]]: transcription repression | ||
* '''Additional information:''' | * '''Additional information:''' | ||
Revision as of 18:20, 31 August 2009
- Description: phospho-alpha-glucosidase
| Gene name | treA |
| Synonyms | treC |
| Essential | no |
| Product | phospho-alpha-glucosidase |
| Function | trehalose utilization |
| Metabolic function and regulation of this protein in SubtiPathways: Sugar catabolism | |
| MW, pI | 65 kDa, 4.895 |
| Gene length, protein length | 1683 bp, 561 aa |
| Immediate neighbours | treP, treR |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Contents
The gene
Basic information
- Locus tag: BSU07810
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Alpha,alpha-trehalose 6-phosphate + H2O = D-glucose + D-glucose 6-phosphate (according to Swiss-Prot)
- Protein family: glycosyl hydrolase 13 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P39795
- KEGG entry: [3]
- E.C. number: 3.2.1.93 3
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant: GP1118 (spc), available in the Stülke lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
