Difference between revisions of "Gdh"
| Line 88: | Line 88: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[glcU]]-[[gdh]]'' {{PubMed|3141376}} |
| − | * '''[[Sigma factor]]:''' [[SigG]] {{PubMed| | + | * '''[[Sigma factor]]:''' [[SigG]] {{PubMed|3141376}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** expressed during sporulation ([[SigG]], [[SpoVT]]) {{PubMed|3141376,8755877}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[SpoVT]]: transcription repression {{PubMed|8755877}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 117: | Line 119: | ||
=References= | =References= | ||
| − | + | <pubmed> 3141376,8755877 21162,,2493633,</pubmed> | |
| − | <pubmed>21162,,2493633 | ||
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 19:52, 19 August 2009
- Description: glucose 1-dehydrogenase (NAD)
| Gene name | gdh |
| Synonyms | |
| Essential | no |
| Product | glucose 1-dehydrogenase (NAD) |
| Function | germination |
| MW, pI | 27 kDa, 5.082 |
| Gene length, protein length | 783 bp, 261 aa |
| Immediate neighbours | glcU, ycnI |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
The gene
Basic information
- Locus tag: BSU03930
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: Beta-D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H (according to Swiss-Prot)
- Protein family: short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Interactions:
- Localization:
Database entries
- Structure:
- UniProt: P12310
- KEGG entry: [3]
- E.C. number: 1.1.1.47
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
I Bagyan, J Hobot, S Cutting
A compartmentalized regulator of developmental gene expression in Bacillus subtilis.
J Bacteriol: 1996, 178(15);4500-7
[PubMed:8755877]
[WorldCat.org]
[DOI]
(P p)
Y Nakatani, W L Nicholson, K D Neitzke, P Setlow, E Freese
Sigma-G RNA polymerase controls forespore-specific expression of the glucose dehydrogenase operon in Bacillus subtilis.
Nucleic Acids Res: 1989, 17(3);999-1017
[PubMed:2493633]
[WorldCat.org]
[DOI]
(P p)
P N Rather, C P Moran
Compartment-specific transcription in Bacillus subtilis: identification of the promoter for gdh.
J Bacteriol: 1988, 170(11);5086-92
[PubMed:3141376]
[WorldCat.org]
[DOI]
(P p)
Y Fujita, R Ramaley, E Freese
Location and properties of glucose dehydrogenase in sporulating cells and spores of Bacillus subtilis.
J Bacteriol: 1977, 132(1);282-93
[PubMed:21162]
[WorldCat.org]
[DOI]
(P p)
