YxaB

• Description: general stress protein, putative exopolysaccaride synthase, important for biofilm formation
  
  

Gene name	yxaB
Synonyms
Essential	no
Product	putative exopolysaccaride synthase
Function	biofilm formation, survival of salt and ethanol stress
MW, pI	39 kDa, 4.525
Gene length, protein length	1029 bp, 343 aa
Immediate neighbours	yxaC, yxaA
Get the DNA and protein sequences (Barbe et al., 2009)
Genetic context This image was kindly provided by SubtiList

The gene

Basic information

• Locus tag: BSU40030

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: polysaccharide pyruvyl transferase family (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• Swiss prot entry: P42101

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: yxaA-yxaB PubMed

• Sigma factor: SigB PubMed

• Regulation: induced by stress (SigB) PubMed
  • repressed during logrithmic growth (AbrB) PubMed

• Regulatory mechanism:
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528] [WorldCat.org] [DOI] (P p)

1. Höper et al. (2005) Comprehensive Characterization of the Contribution of Individual SigB-Dependent General Stress Genes to Stress Resistance of Bacillus subtilis. J. Bact. 187: 2810-2826 PubMed
2. Author1, Author2 & Author3 (year) Title Journal volume: page-page. PubMed