Difference between revisions of "S-box Element"
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Revision as of 18:10, 7 June 2009
The S-box element is a riboswitch that controls different genes of sulphur metabolism in response to the presence of S-adenosylmethionine.
- Upon binding of SAM, the riboswitch adopts a terminator structure resulting in transcription termination.
- In the aabsence of SAM, the riboswitch has the antitermination structure that allows transcription elongation into the controlled gene/ operon.
Genes controlled by a S-box
- cysH-cysP-sat-cysC-ylnD-ylnE-ylnF
- metE
- metI-metC
- metK
- metN-metP-metQ
- mtnK-mtnS
- mtnW-mtnX-mtnB-mtnD
- yitJ-yitI-yitH
- yoaD-yoaC-yoaB
- yxjG
- yxjH
References
Jerneja Tomsic, Brooke A McDaniel, Frank J Grundy, Tina M Henkin
Natural variability in S-adenosylmethionine (SAM)-dependent riboswitches: S-box elements in bacillus subtilis exhibit differential sensitivity to SAM In vivo and in vitro.
J Bacteriol: 2008, 190(3);823-33
[PubMed:18039762]
[WorldCat.org]
[DOI]
(I p)
T M Henkin, F J Grundy
Sensing metabolic signals with nascent RNA transcripts: the T box and S box riboswitches as paradigms.
Cold Spring Harb Symp Quant Biol: 2006, 71;231-7
[PubMed:17381302]
[WorldCat.org]
[DOI]
(P p)
Brooke A Murphy McDaniel, Frank J Grundy, Irina Artsimovitch, Tina M Henkin
Transcription termination control of the S box system: direct measurement of S-adenosylmethionine by the leader RNA.
Proc Natl Acad Sci U S A: 2003, 100(6);3083-8
[PubMed:12626738]
[WorldCat.org]
[DOI]
(P p)
