Difference between revisions of "ClpE"
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* '''Regulation:''' | * '''Regulation:''' | ||
− | * '''Regulatory mechanism:''' | + | * '''Regulatory mechanism:''' negative regulation by [[CtsR]] [http://www.ncbi.nlm.nih.gov/pubmed/11179229 PubMed], [http://www.ncbi.nlm.nih.gov/pubmed/16163393 PubMed], [http://www.ncbi.nlm.nih.gov/pubmed/17380125 PubMed] |
− | * '''Additional information:''' | + | * '''Additional information:''' |
=Biological materials = | =Biological materials = |
Revision as of 21:55, 28 April 2009
- Description: ATP-dependent Clp protease-like (class III stress gene)
Gene name | clpE |
Synonyms | ykvH |
Essential | no |
Product | ATP-dependent Clp protease-like |
Function | protein degradation |
MW, pI | 77 kDa, 5.135 |
Gene length, protein length | 2097 bp, 699 aa |
Immediate neighbours | motA, ykvI |
Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context This image was kindly provided by SubtiList
|
Contents
The gene
Basic information
- Coordinates:
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: ATPase/chaperone
Extended information on the protein
- Kinetic information:
- Domains: AAA-ATPase PFAM
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: expressed after heat shock, localization in cytoplasmic polar clusters, excluded from the nucleoid, colocalization with ClpP Pubmed
Database entries
- Structure:
- Swiss prot entry: O31673
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Additional information:
Biological materials
- Expression vector:
- lacZ fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Leendert Hamoen, Newcastle University, UK homepage