Difference between revisions of "FlgM"
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− | * '''Description:''' anti-[[SigD]], regulation of flagellin, motility | + | * '''Description:''' anti-[[SigD]], regulation of flagellin, [[motility and chemotaxis]] <br/><br/> |
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* '''[[Localization]]:''' | * '''[[Localization]]:''' | ||
+ | ** secreted and extracellularly degraded by the proteases [[Epr]] and [[WprA]] {{PubMed|25313396}} | ||
+ | ** secretion of FlgM requires the [[FliF]]/[[FliG]] basal body proteins, the flagellar type III export apparatus components [[FliO]], [[FliP]], [[FliQ]], [[FliR]], [[FlhA]], and [[FlhB]], and the substrate specificity switch regulator [[FliK]] {{PubMed|25313396}} | ||
=== Database entries === | === Database entries === | ||
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<pubmed>25251856 </pubmed> | <pubmed>25251856 </pubmed> | ||
==Original Publications== | ==Original Publications== | ||
− | <pubmed>8955328,19898538 8412657 8045879 , 20233303 10207036 8655488 23352839 21736639</pubmed> | + | <pubmed>8955328,19898538 8412657 8045879 , 20233303 10207036 8655488 23352839 21736639 25313396 </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] |
Revision as of 14:33, 19 October 2014
- Description: anti-SigD, regulation of flagellin, motility and chemotaxis
Gene name | flgM |
Synonyms | |
Essential | no |
Product | anti-SigD |
Function | control of SigD activity |
Gene expression levels in SubtiExpress: flgM | |
Interactions involving this protein in SubtInteract: FlgM | |
MW, pI | 9 kDa, 9.918 |
Gene length, protein length | 264 bp, 88 aa |
Immediate neighbours | flgN, yvyF |
Sequences | Protein DNA DNA_with_flanks |
Genetic context This image was kindly provided by SubtiList
| |
Expression at a glance PubMed |
Contents
Categories containing this gene/protein
sigma factors and their control, motility and chemotaxis
This gene is a member of the following regulons
ComK regulon, DegU regulon, ScoC regulon, SigD regulon
The gene
Basic information
- Locus tag: BSU35430
Phenotypes of a mutant
Database entries
- BsubCyc: BSU35430
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: flgM family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Modification:
- Effectors of protein activity:
Database entries
- BsubCyc: BSU35430
- Structure:
- UniProt: P39809
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon:
- Regulation:
- Regulatory mechanism:
- Regulatory mechanism:
- Additional information:
Biological materials
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Sampriti Mukherjee, Daniel B Kearns
The structure and regulation of flagella in Bacillus subtilis.
Annu Rev Genet: 2014, 48;319-40
[PubMed:25251856]
[WorldCat.org]
[DOI]
(I p)
Original Publications