Difference between revisions of "SpsL"

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= This gene is a member of the following [[regulons]] =
 
= This gene is a member of the following [[regulons]] =
 +
{{SubtiWiki regulon|[[GerE regulon]]}},
 
{{SubtiWiki regulon|[[SigK regulon]]}}
 
{{SubtiWiki regulon|[[SigK regulon]]}}
  
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=== Additional information===
 
=== Additional information===
 
 
 
  
 
=The protein=
 
=The protein=
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* '''Regulation:'''  
 
* '''Regulation:'''  
** expressed late during sporulation in the mother cell ([[SigK]]) {{PubMed|15383836}}  
+
** expressed late during sporulation in the mother cell ([[SigK]], [[GerE]]) {{PubMed|25239894,15383836}}  
  
 
* '''Regulatory mechanism:'''  
 
* '''Regulatory mechanism:'''  
 +
** [[GerE]]: transcription activation {{PubMed|25239894,15383836}}
  
 
* '''Additional information:'''
 
* '''Additional information:'''
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=References=
 
=References=
<pubmed>9353933 15383836 22960854 </pubmed>
+
<pubmed>9353933 15383836 22960854 25239894</pubmed>
 
[[Category:Protein-coding genes]]
 
[[Category:Protein-coding genes]]

Revision as of 11:03, 23 September 2014

  • Description: dTDP -4-dehydrorhamnose-3,5-epimerase, spore coat polysaccharide synthesis

Gene name spsL
Synonyms ipa-73d
Essential no
Product dTDP -4-dehydrorhamnose-3,5-epimerase
Function rhamnose biosynthesis, spore coat polysaccharide synthesis
Gene expression levels in SubtiExpress: spsL
MW, pI 17 kDa, 4.878
Gene length, protein length 453 bp, 151 aa
Immediate neighbours sivA, spsK
Sequences Protein DNA DNA_with_flanks
Genetic context
SpsL context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
SpsL expression.png















Categories containing this gene/protein

miscellaneous metabolic pathways, sporulation proteins

This gene is a member of the following regulons

GerE regulon, SigK regulon

The gene

Basic information

  • Locus tag: BSU37810

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 3RYK (dTDP-4-dehydrorhamnose 3,5-epimerase (rfbC) from Bacillus anthracis str. Ames with TDP and PPi bound, 32% identity, 56% similarity)
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulation:
    • expressed late during sporulation in the mother cell (SigK, GerE) PubMed
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References