YsbB

• Description: putative peptidoglycan hydrolase, probably involved in cell wall turnover
  
  

Gene name	ysbB
Synonyms
Essential	no
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: ysbB
MW, pI	24 kDa, 9.81
Gene length, protein length	693 bp, 231 aa
Immediate neighbours	yscB, ysbA
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

cell wall degradation/ turnover

The gene

Basic information

• Locus tag: BSU28900

Phenotypes of a mutant

• • ysbAB mutant is delayed in pellicle formation (Chen et al)
  • ywbHG-yxaKC-ysbAB triple mutant is severely delayed in pellicle formation (Chen et al)

Database entries

• BsubCyc: BSU28900

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family: LrgB subfamily (according to Swiss-Prot)

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• BsubCyc: BSU28900

• Structure:

• UniProt: P94516

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon:
  • ysbA-ysbB PubMed
  • ysbB PubMed

• Expression browser: ysbB PubMed

• Sigma factor:

• Regulation:
  • ysbAB expression is induced by acetate (Chen et al)

• Regulatory mechanism:

• Additional information:
  • the mRNA is substantially stabilized upon depletion of RNase Y PubMed
  • the expression of the ysbA-ysbB operon is strongly increased in a cshA mutant PubMed

Biological materials

• Mutant:
  • GP1554 (ysbA-ysbB::spc), available in Jörg Stülke's lab

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody: