Difference between revisions of "DctS"
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=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU04450&redirect=T BSU04450] | ||
* '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/dctSRP.html] | * '''DBTBS entry:''' [http://dbtbs.hgc.jp/COG/prom/dctSRP.html] | ||
| Line 96: | Line 97: | ||
=== Database entries === | === Database entries === | ||
| + | * '''BsubCyc:''' [http://bsubcyc.org/BSUB/NEW-IMAGE?type=NIL&object=BSU04450&redirect=T BSU04450] | ||
* '''Structure:''' | * '''Structure:''' | ||
Revision as of 13:01, 2 April 2014
- Description: two-component sensor kinase, regulation of the dctS-dctR-dctP operon
| Gene name | dctS |
| Synonyms | ydbF |
| Essential | no |
| Product | two-component sensor kinase |
| Function | regulation of the dctS-dctR-dctP operon |
| Gene expression levels in SubtiExpress: dctS | |
| Interactions involving this protein in SubtInteract: DctS | |
| Metabolic function and regulation of this protein in SubtiPathways: dctS | |
| MW, pI | 59 kDa, 6.198 |
| Gene length, protein length | 1605 bp, 535 aa |
| Immediate neighbours | dctB, dctR |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
utilization of specific carbon sources, protein modification, transcription factors and their control, membrane proteins, phosphoproteins
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU04450
Phenotypes of a mutant
Database entries
- BsubCyc: BSU04450
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: autophosphorylation, phosphorylation of DctR
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains: two transmembrane segments, C-terminal histidine phosphotransferase domain
- Modification: autophosphorylation on a His residue
- Cofactors:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- BsubCyc: BSU04450
- Structure:
- UniProt: P96601
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant: GP225 (dctS::cat), available in Jörg Stülke's lab
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Sabrina Graf, Dominik Schmieden, Karolin Tschauner, Sabine Hunke, Gottfried Unden
The sensor kinase DctS forms a tripartite sensor unit with DctB and DctA for sensing C4-dicarboxylates in Bacillus subtilis.
J Bacteriol: 2014, 196(5);1084-93
[PubMed:24375102]
[WorldCat.org]
[DOI]
(I p)
Kei Asai, Sang-Hoon Baik, Yasuhiro Kasahara, Shigeki Moriya, Naotake Ogasawara
Regulation of the transport system for C4-dicarboxylic acids in Bacillus subtilis.
Microbiology (Reading): 2000, 146 ( Pt 2);263-271
[PubMed:10708364]
[WorldCat.org]
[DOI]
(P p)
C Fabret, V A Feher, J A Hoch
Two-component signal transduction in Bacillus subtilis: how one organism sees its world.
J Bacteriol: 1999, 181(7);1975-83
[PubMed:10094672]
[WorldCat.org]
[DOI]
(P p)
