YddT

• Description: unknown essential gene
  
  

Gene name	yddT
Synonyms
Essential	yes PubMed
Product	unknown
Function	unknown
Gene expression levels in SubtiExpress: yddT
MW, pI	25 kDa, 9.546
Gene length, protein length	684 bp, 228 aa
Immediate neighbours	ydzM, ydzN
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed 500px

Categories containing this gene/protein

essential genes, proteins of unknown function

This gene is a member of the following regulons

AbrB regulon

The gene

Basic information

• Locus tag: BSU05100

Phenotypes of a mutant

essential PubMed

Database entries

• DBTBS entry: no entry

• SubtiList entry: [1]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity:

• Protein family:

• Paralogous protein(s): almost identical to the protein YomL encoded by the prophage SPß (the two proteins differ in only 4 out of 228 amino acids)

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity:

• Interactions:

• Localization:

Database entries

• Structure:

• UniProt: P96657

• KEGG entry: [2]

• E.C. number:

Expression and regulation

• Operon: yddT PubMed

• Expression browser: yddT PubMed

• Sigma factor:

• Regulation:

• Regulatory mechanism:
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:
  • BP116 (yddT::spc), available in Fabian Commichau's lab

• Expression vector:
  • IPTG inducible expression of Strep-yddT in E. coli: pGP2581 (in pGP172), available in Jörg Stülke's lab

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Fabian M Commichau, Nico Pietack, Jörg Stülke
Essential genes in Bacillus subtilis: a re-evaluation after ten years.
Mol Biosyst: 2013, 9(6);1068-75
[PubMed:23420519] [WorldCat.org] [DOI] (I p)

Onuma Chumsakul, Hiroki Takahashi, Taku Oshima, Takahiro Hishimoto, Shigehiko Kanaya, Naotake Ogasawara, Shu Ishikawa
Genome-wide binding profiles of the Bacillus subtilis transition state regulator AbrB and its homolog Abh reveals their interactive role in transcriptional regulation.
Nucleic Acids Res: 2011, 39(2);414-28
[PubMed:20817675] [WorldCat.org] [DOI] (I p)

Helena B Thomaides, Ella J Davison, Lisa Burston, Hazel Johnson, David R Brown, Alison C Hunt, Jeffery Errington, Lloyd Czaplewski
Essential bacterial functions encoded by gene pairs.
J Bacteriol: 2007, 189(2);591-602
[PubMed:17114254] [WorldCat.org] [DOI] (P p)