Difference between revisions of "MutL"

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* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=mutL_1778337_1780220_1 mutL] {{PubMed|22383849}}
 
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=mutL_1778337_1780220_1 mutL] {{PubMed|22383849}}
  
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* '''Regulation:'''  
 
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Revision as of 13:36, 27 May 2013

  • Description: DNA mismatch repair

Gene name mutL
Synonyms
Essential no
Product DNA mismatch repair
Function DNA repair
Gene expression levels in SubtiExpress: mutL
Interactions involving this protein in SubtInteract: MutL
MW, pI 70 kDa, 5.583
Gene length, protein length 1881 bp, 627 aa
Immediate neighbours mutS, ymzD
Sequences Protein DNA DNA_with_flanks
Genetic context
MutL context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
MutL expression.png















Categories containing this gene/protein

DNA repair/ recombination

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU17050

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family: DNA mismatch repair mutL/hexB family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:
  • Localization:
    • forms foci at midcell position, the frequency of foci increases upon mismatch formation PubMed

Database entries

  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:

Biological materials

  • Mutant: GP1190 (del mutSL::aphA3) available in the Stülke lab
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References