Difference between revisions of "LigD"
| Line 41: | Line 41: | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| − | {{SubtiWiki regulon|[[SigG regulon]]}} | + | {{SubtiWiki regulon|[[SigG regulon]]}}, |
| + | {{SubtiWiki regulon|[[SpoVT regulon]]}} | ||
| + | |||
=The gene= | =The gene= | ||
| Line 76: | Line 78: | ||
* '''Kinetic information:''' | * '''Kinetic information:''' | ||
| − | * '''Domains:''' | + | * '''Domains:''' C-terminal DNA ligase catalytic domain linked to an N-terminal polymerase domain {{PubMed|23691176}} |
* '''Modification:''' | * '''Modification:''' | ||
| Line 106: | Line 108: | ||
* '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ykoU_1404518_1406353_-1 ykoU] {{PubMed|22383849}} | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=ykoU_1404518_1406353_-1 ykoU] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' [[SigG]] {{PubMed|16497325}} | + | * '''[[Sigma factor]]:''' [[SigG]] {{PubMed|16497325}} |
| − | * '''Regulation:''' expressed during sporulation in the forespore ([[SigG]]) {{PubMed|16497325}} | + | * '''Regulation:''' |
| + | ** expressed during [[sporulation]] in the forespore ([[SigG]], [[SpoVT]]) {{PubMed|16497325}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[SpoVT]]: transcription activation {{PubMed|16497325}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 134: | Line 138: | ||
=References= | =References= | ||
| − | <pubmed>16497325,, </pubmed> | + | <pubmed>16497325, 23691176, </pubmed> |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 10:23, 23 May 2013
- Description: confers dry-heat resistance to dormant spores PubMed, similar to ATP-dependent DNA ligase
| Gene name | ykoU |
| Synonyms | |
| Essential | no |
| Product | unknown |
| Function | confers dry-heat resistance to dormant spores |
| Gene expression levels in SubtiExpress: ykoU | |
| MW, pI | 70 kDa, 6.646 |
| Gene length, protein length | 1833 bp, 611 aa |
| Immediate neighbours | ykoT, ykoV |
| Sequences | Protein DNA DNA_with_flanks |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU13400
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains: C-terminal DNA ligase catalytic domain linked to an N-terminal polymerase domain PubMed
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O34398
- KEGG entry: [2]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- expressed during sporulation in the forespore (SigG, SpoVT) PubMed
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Miguel de Vega
The minimal Bacillus subtilis nonhomologous end joining repair machinery.
PLoS One: 2013, 8(5);e64232
[PubMed:23691176]
[WorldCat.org]
[DOI]
(I e)
Stephanie T Wang, Barbara Setlow, Erin M Conlon, Jessica L Lyon, Daisuke Imamura, Tsutomu Sato, Peter Setlow, Richard Losick, Patrick Eichenberger
The forespore line of gene expression in Bacillus subtilis.
J Mol Biol: 2006, 358(1);16-37
[PubMed:16497325]
[WorldCat.org]
[DOI]
(P p)
