RapK

• Description: response regulator aspartate phosphatase, controls ComA activity
  
  

Gene name	rapK
Synonyms	yobG
Essential	no
Product	response regulator aspartate phosphatase
Function	control of ComA activity
Gene expression levels in SubtiExpress: rapK
Interactions involving this protein in SubtInteract: RapK
MW, pI	43 kDa, 5.06
Gene length, protein length	1113 bp, 371 aa
Immediate neighbours	yozZ, phrK
Sequences	Protein DNA DNA_with_flanks
Genetic context This image was kindly provided by SubtiList
Expression at a glance   PubMed

Categories containing this gene/protein

genetic competence, protein modification, transcription factors and their control, quorum sensing

This gene is a member of the following regulons

AbrB regulon, SigH regulon

The gene

Basic information

• Locus tag: BSU18910

Database entries

• DBTBS entry: [1]

• SubtiList entry: [2]

The protein

Basic information/ Evolution

• Catalyzed reaction/ biological activity: control of ComA activity PubMed

• Protein family:

• Paralogous protein(s):

Extended information on the protein

• Kinetic information:

• Domains:

• Modification:

• Cofactor(s):

• Effectors of protein activity: binding of PhrK inhibits RapK activity PubMed

• Interactions:
  • RapK-PhrK PubMed

• Localization:

Database entries

• Structure:

• UniProt: O34930

• KEGG entry: [3]

• E.C. number:

Expression and regulation

• Operon: rapK-phrK PubMed

• Expression browser: rapK PubMed

• Sigma factor: SigH PubMed

• Regulation:

• Regulatory mechanism:
  • AbrB: transcription repression PubMed

• Additional information:

Biological materials

• Mutant:

• Expression vector:

• lacZ fusion:

• GFP fusion:

• two-hybrid system:

• Antibody:

References

Additional publications: PubMed

Jennifer M Auchtung, Catherine A Lee, Alan D Grossman
Modulation of the ComA-dependent quorum response in Bacillus subtilis by multiple Rap proteins and Phr peptides.
J Bacteriol: 2006, 188(14);5273-85
[PubMed:16816200] [WorldCat.org] [DOI] (P p)

R S McQuade, N Comella, A D Grossman
Control of a family of phosphatase regulatory genes (phr) by the alternate sigma factor sigma-H of Bacillus subtilis.
J Bacteriol: 2001, 183(16);4905-9
[PubMed:11466295] [WorldCat.org] [DOI] (P p)