Difference between revisions of "NtdC"
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|style="background:#ABCDEF;" align="center"|'''Function''' || synthesis of the antibiotic kanosamine | |style="background:#ABCDEF;" align="center"|'''Function''' || synthesis of the antibiotic kanosamine | ||
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| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU10530 ntdC] |
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 39 kDa, 6.227 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 39 kDa, 6.227 | ||
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[glcP]]'', ''[[ntdB]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[glcP]]'', ''[[ntdB]]'' | ||
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| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU10530 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU10530 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU10530 Advanced_DNA] |
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Revision as of 12:29, 13 May 2013
- Description: NAD-dependent glucose-6-phosphate dehydrogenase
| Gene name | ntdC |
| Synonyms | yhjJ |
| Essential | no |
| Product | NAD-dependent glucose-6-phosphate dehydrogenase |
| Function | synthesis of the antibiotic kanosamine |
| Gene expression levels in SubtiExpress: ntdC | |
| MW, pI | 39 kDa, 6.227 |
| Gene length, protein length | 1050 bp, 350 aa |
| Immediate neighbours | glcP, ntdB |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
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Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, biosynthesis of antibacterial compounds
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU10530
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- glucose-6-phosphate + NAD --> 3-oxo-d-glucose-6-phosphate + NADH(2) PubMed
- Protein family: gfo/idh/mocA family (according to Swiss-Prot)
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- NAD(+) PubMed
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: O07564
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Reviews
Takashi Inaoka, Kozo Ochi
Activation of dormant secondary metabolism neotrehalosadiamine synthesis by an RNA polymerase mutation in Bacillus subtilis.
Biosci Biotechnol Biochem: 2011, 75(4);618-23
[PubMed:21512256]
[WorldCat.org]
[DOI]
(I p)
Original publications
