Difference between revisions of "BacF"
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|style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of the antibiotic bacilysin | |style="background:#ABCDEF;" align="center"|'''Function''' || biosynthesis of the antibiotic bacilysin | ||
|- | |- | ||
| − | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http:// | + | |colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU37690 bacF] |
|- | |- | ||
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 44 kDa, 5.347 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 44 kDa, 5.347 | ||
| Line 22: | Line 22: | ||
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[bacG]]'', ''[[bacE]]'' | |style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[bacG]]'', ''[[bacE]]'' | ||
|- | |- | ||
| − | | | + | |style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU37690 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU37690 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU37690 Advanced_DNA] |
|- | |- | ||
|colspan="2" | '''Genetic context''' <br/> [[Image:ywfG_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:ywfG_context.gif]] | ||
Revision as of 14:08, 13 May 2013
- Description: aminotransferase involved in bacilysin synthesis
| Gene name | bacF |
| Synonyms | ywfG, ipa-85d |
| Essential | no |
| Product | aminotransferase |
| Function | biosynthesis of the antibiotic bacilysin |
| Gene expression levels in SubtiExpress: bacF | |
| MW, pI | 44 kDa, 5.347 |
| Gene length, protein length | 1197 bp, 399 aa |
| Immediate neighbours | bacG, bacE |
| Sequences | Protein DNA Advanced_DNA |
Genetic context 
This image was kindly provided by SubtiList
| |
Expression at a glance PubMed
| |
Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, biosynthesis of antibacterial compounds
This gene is a member of the following regulons
AbrB regulon, CodY regulon, ScoC regulon
The gene
Basic information
- Locus tag: BSU37690
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: [1]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity: YwfG catalyzes transamination of tetrahydro-4-hydroxyphenylpyruvate (with L-Phe as amino donor), to form tetrahydrotyrosine PubMed
- Protein family: class-I pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
- Localization: cytoplasm (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P39643
- KEGG entry: [2]
- E.C. number: 2.6.1.1
Additional information
Expression and regulation
- Regulation:
- Regulatory mechanism:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Takashi Inaoka, Kozo Ochi
Scandium stimulates the production of amylase and bacilysin in Bacillus subtilis.
Appl Environ Microbiol: 2011, 77(22);8181-3
[PubMed:21948839]
[WorldCat.org]
[DOI]
(I p)
Türkan Ebru Köroğlu, Ismail Oğülür, Seval Mutlu, Ayten Yazgan-Karataş, Gülay Ozcengiz
Global regulatory systems operating in Bacilysin biosynthesis in Bacillus subtilis.
J Mol Microbiol Biotechnol: 2011, 20(3);144-55
[PubMed:21709425]
[WorldCat.org]
[DOI]
(I p)
Sarah A Mahlstedt, Christopher T Walsh
Investigation of anticapsin biosynthesis reveals a four-enzyme pathway to tetrahydrotyrosine in Bacillus subtilis.
Biochemistry: 2010, 49(5);912-23
[PubMed:20052993]
[WorldCat.org]
[DOI]
(I p)
Takashi Inaoka, Guojun Wang, Kozo Ochi
ScoC regulates bacilysin production at the transcription level in Bacillus subtilis.
J Bacteriol: 2009, 191(23);7367-71
[PubMed:19801406]
[WorldCat.org]
[DOI]
(I p)
Ayten Yazgan Karataş, Seçil Cetin, Gülay Ozcengiz
The effects of insertional mutations in comQ, comP, srfA, spo0H, spo0A and abrB genes on bacilysin biosynthesis in Bacillus subtilis.
Biochim Biophys Acta: 2003, 1626(1-3);51-6
[PubMed:12697329]
[WorldCat.org]
(P p)
Takashi Inaoka, Kosaku Takahashi, Mayumi Ohnishi-Kameyama, Mitsuru Yoshida, Kozo Ochi
Guanine nucleotides guanosine 5'-diphosphate 3'-diphosphate and GTP co-operatively regulate the production of an antibiotic bacilysin in Bacillus subtilis.
J Biol Chem: 2003, 278(4);2169-76
[PubMed:12372825]
[WorldCat.org]
[DOI]
(P p)
