Difference between revisions of "SpoVAEA"
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|style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/genE_protein.txt Protein sequence]''' | |style="background:#FAF8CC;" align="center"|'''[http://subtiwiki.uni-goettingen.de/genE_protein.txt Protein sequence]''' | ||
|- | |- | ||
| − | |colspan="2" | '''Genetic context''' <br/> [[Image: | + | |colspan="2" | '''Genetic context''' <br/> [[Image:spoVAE_context.gif]] |
| + | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
|- | |- | ||
|} | |} | ||
| Line 37: | Line 38: | ||
= This gene is a member of the following [[regulons]] = | = This gene is a member of the following [[regulons]] = | ||
| − | + | {{SubtiWiki regulon|[[SigG regulon]]}}, | |
| + | {{SubtiWiki regulon|[[SpoVT regulon]]}} | ||
=The gene= | =The gene= | ||
| Line 97: | Line 99: | ||
=Expression and regulation= | =Expression and regulation= | ||
| − | * '''Operon:''' | + | * '''Operon:''' ''[[spoVAA]]-[[spoVAB]]-[[spoVAC]]-[[spoVAD]]-[[spoVAEB]]-[[spoVAEA]]-[[spoVAF]]-[[lysA]]'' {{PubMed|7934830}} |
| + | |||
| + | * '''Expression browser:''' [http://genome.jouy.inra.fr/cgi-bin/seb/viewdetail.py?id=spoVAEA_2439804_2440415_-1 spoVAEA] {{PubMed|22383849}} | ||
| − | * '''Sigma factor:''' | + | * '''[[Sigma factor]]:''' [[SigG]] {{PubMed|15699190,1903432}} |
* '''Regulation:''' | * '''Regulation:''' | ||
| + | ** expressed late during sporulation in the forespore ([[SigG]], [[SpoVT]]) {{PubMed|15699190,1903432,8755877}} | ||
* '''Regulatory mechanism:''' | * '''Regulatory mechanism:''' | ||
| + | ** [[SpoVT]]: transcription activation {{PubMed|8755877}} | ||
* '''Additional information:''' | * '''Additional information:''' | ||
| Line 122: | Line 128: | ||
=Labs working on this gene/protein= | =Labs working on this gene/protein= | ||
| + | * [[Peter Setlow]], University of Connecticut Health Center, USA | ||
=Your additional remarks= | =Your additional remarks= | ||
| Line 127: | Line 134: | ||
=References= | =References= | ||
| − | + | <pubmed>17573930,3114420,11751839,15451103,3926949,17158659,6432957,7934830 22328679 15699190,1903432,8755877</pubmed> | |
[[Category:Protein-coding genes]] | [[Category:Protein-coding genes]] | ||
Revision as of 16:34, 25 January 2013
- Description: stage V sporulation germinant protein
| Gene name | spoVAEA |
| Synonyms | |
| Essential | no |
| Product | stage V sporulation germinant protein |
| Function | spore germination |
| Gene expression levels in SubtiExpress: spoVAEA | |
| MW, pI | 22 kDa, 5.150 |
| Gene length, protein length | 609 bp, 203 aa |
| Immediate neighbours | spoVAF, spoVAEB |
| Gene sequence (+200bp) | Protein sequence |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU23401
Phenotypes of a mutant
Database entries
- DBTBS entry: no entry
- SubtiList entry: no entry
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure:
- UniProt: C0H449
- KEGG entry:
- E.C. number:
Additional information
Expression and regulation
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
- Peter Setlow, University of Connecticut Health Center, USA
Your additional remarks
References
Yunfeng Li, Andrew Davis, George Korza, Pengfei Zhang, Yong-qing Li, Barbara Setlow, Peter Setlow, Bing Hao
Role of a SpoVA protein in dipicolinic acid uptake into developing spores of Bacillus subtilis.
J Bacteriol: 2012, 194(8);1875-84
[PubMed:22328679]
[WorldCat.org]
[DOI]
(I p)
Venkata Ramana Vepachedu, Peter Setlow
Analysis of interactions between nutrient germinant receptors and SpoVA proteins of Bacillus subtilis spores.
FEMS Microbiol Lett: 2007, 274(1);42-7
[PubMed:17573930]
[WorldCat.org]
[DOI]
(P p)
Venkata Ramana Vepachedu, Peter Setlow
Role of SpoVA proteins in release of dipicolinic acid during germination of Bacillus subtilis spores triggered by dodecylamine or lysozyme.
J Bacteriol: 2007, 189(5);1565-72
[PubMed:17158659]
[WorldCat.org]
[DOI]
(P p)
Leif Steil, Mónica Serrano, Adriano O Henriques, Uwe Völker
Genome-wide analysis of temporally regulated and compartment-specific gene expression in sporulating cells of Bacillus subtilis.
Microbiology (Reading): 2005, 151(Pt 2);399-420
[PubMed:15699190]
[WorldCat.org]
[DOI]
(P p)
Venkata Ramana Vepachedu, Peter Setlow
Analysis of the germination of spores of Bacillus subtilis with temperature sensitive spo mutations in the spoVA operon.
FEMS Microbiol Lett: 2004, 239(1);71-7
[PubMed:15451103]
[WorldCat.org]
[DOI]
(P p)
Federico Tovar-Rojo, Monica Chander, Barbara Setlow, Peter Setlow
The products of the spoVA operon are involved in dipicolinic acid uptake into developing spores of Bacillus subtilis.
J Bacteriol: 2002, 184(2);584-7
[PubMed:11751839]
[WorldCat.org]
[DOI]
(P p)
I Bagyan, J Hobot, S Cutting
A compartmentalized regulator of developmental gene expression in Bacillus subtilis.
J Bacteriol: 1996, 178(15);4500-7
[PubMed:8755877]
[WorldCat.org]
[DOI]
(P p)
V Azevedo, A Sorokin, S D Ehrlich, P Serror
The transcriptional organization of the Bacillus subtilis 168 chromosome region between the spoVAF and serA genetic loci.
Mol Microbiol: 1993, 10(2);397-405
[PubMed:7934830]
[WorldCat.org]
[DOI]
(P p)
B Moldover, P J Piggot, M D Yudkin
Identification of the promoter and the transcriptional start site of the spoVA operon of Bacillus subtilis and Bacillus licheniformis.
J Gen Microbiol: 1991, 137(3);527-31
[PubMed:1903432]
[WorldCat.org]
[DOI]
(P p)
J Errington, J Mandelstam
Use of a lacZ gene fusion to determine the dependence pattern and the spore compartment expression of sporulation operon spoVA in spo mutants of Bacillus subtilis.
J Gen Microbiol: 1986, 132(11);2977-85
[PubMed:3114420]
[WorldCat.org]
[DOI]
(P p)
P Fort, J Errington
Nucleotide sequence and complementation analysis of a polycistronic sporulation operon, spoVA, in Bacillus subtilis.
J Gen Microbiol: 1985, 131(5);1091-105
[PubMed:3926949]
[WorldCat.org]
[DOI]
(P p)
J Errington, J Mandelstam
Genetic and phenotypic characterization of a cluster of mutations in the spoVA locus of Bacillus subtilis.
J Gen Microbiol: 1984, 130(8);2115-21
[PubMed:6432957]
[WorldCat.org]
[DOI]
(P p)
