Difference between revisions of "Gdh"

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|style="background:#ABCDEF;" align="center"|'''Function''' || germination  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || germination  
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU03930 gdh]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU03930 gdh]
 
|-
 
|-
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 27 kDa, 5.082   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 27 kDa, 5.082   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[glcU]]'', ''[[ycnI]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[glcU]]'', ''[[ycnI]]''
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12201&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU03930 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU03930 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU03930 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:gdh_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:gdh_context.gif]]

Revision as of 12:09, 13 May 2013

  • Description: glucose 1-dehydrogenase (NAD)

Gene name gdh
Synonyms
Essential no
Product glucose 1-dehydrogenase (NAD)
Function germination
Gene expression levels in SubtiExpress: gdh
MW, pI 27 kDa, 5.082
Gene length, protein length 783 bp, 261 aa
Immediate neighbours glcU, ycnI
Sequences Protein DNA Advanced_DNA
Genetic context
Gdh context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Gdh expression.png
























Categories containing this gene/protein

germination

This gene is a member of the following regulons

SigG regulon, SpoVT regulon

The gene

Basic information

  • Locus tag: BSU03930

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: Beta-D-glucose + NAD(P)+ = D-glucono-1,5-lactone + NAD(P)H (according to Swiss-Prot)
  • Protein family: short-chain dehydrogenases/reductases (SDR) family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]

Additional information

Expression and regulation

  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

I Bagyan, J Hobot, S Cutting
A compartmentalized regulator of developmental gene expression in Bacillus subtilis.
J Bacteriol: 1996, 178(15);4500-7
[PubMed:8755877] [WorldCat.org] [DOI] (P p)

Y Nakatani, W L Nicholson, K D Neitzke, P Setlow, E Freese
Sigma-G RNA polymerase controls forespore-specific expression of the glucose dehydrogenase operon in Bacillus subtilis.
Nucleic Acids Res: 1989, 17(3);999-1017
[PubMed:2493633] [WorldCat.org] [DOI] (P p)

P N Rather, C P Moran
Compartment-specific transcription in Bacillus subtilis: identification of the promoter for gdh.
J Bacteriol: 1988, 170(11);5086-92
[PubMed:3141376] [WorldCat.org] [DOI] (P p)

Y Fujita, R Ramaley, E Freese
Location and properties of glucose dehydrogenase in sporulating cells and spores of Bacillus subtilis.
J Bacteriol: 1977, 132(1);282-93
[PubMed:21162] [WorldCat.org] [DOI] (P p)