Difference between revisions of "SpoIIIAB"

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|style="background:#ABCDEF;" align="center"|'''Function''' || activation of [[SigG]]
 
|style="background:#ABCDEF;" align="center"|'''Function''' || activation of [[SigG]]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU24420 spoIIIAB]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU24420 spoIIIAB]
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 19 kDa, 9.214   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 19 kDa, 9.214   
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spoIIIAC]]'', ''[[spoIIIAA]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[spoIIIAC]]'', ''[[spoIIIAA]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB14373&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU24420 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU24420 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU24420 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:spoIIIAB_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:spoIIIAB_context.gif]]

Revision as of 13:16, 13 May 2013

  • Description: component of the SpoIIIA-SpoIIQ type III secretion system residing in the forespore membrane, required for SigG activation

Gene name spoIIIAB
Synonyms
Essential no
Product component of a type III secretion system
Function activation of SigG
Gene expression levels in SubtiExpress: spoIIIAB
MW, pI 19 kDa, 9.214
Gene length, protein length 513 bp, 171 aa
Immediate neighbours spoIIIAC, spoIIIAA
Sequences Protein DNA Advanced_DNA
Genetic context
SpoIIIAB context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
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Categories containing this gene/protein

protein secretion, sporulation proteins, membrane proteins

This gene is a member of the following regulons

SigE regulon, SpoIIID regulon

The gene

Basic information

  • Locus tag: BSU24420

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Thierry Doan, Cecile Morlot, Jeffrey Meisner, Monica Serrano, Adriano O Henriques, Charles P Moran, David Z Rudner
Novel secretion apparatus maintains spore integrity and developmental gene expression in Bacillus subtilis.
PLoS Genet: 2009, 5(7);e1000566
[PubMed:19609349] [WorldCat.org] [DOI] (I p)

Amy H Camp, Richard Losick
A novel pathway of intercellular signalling in Bacillus subtilis involves a protein with similarity to a component of type III secretion channels.
Mol Microbiol: 2008, 69(2);402-17
[PubMed:18485064] [WorldCat.org] [DOI] (I p)

N Illing, J Errington
The spoIIIA operon of Bacillus subtilis defines a new temporal class of mother-cell-specific sporulation genes under the control of the sigma E form of RNA polymerase.
Mol Microbiol: 1991, 5(8);1927-40
[PubMed:1766372] [WorldCat.org] [DOI] (P p)