Difference between revisions of "Dat"

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|style="background:#ABCDEF;" align="center"|'''Function''' || peptidoglycan precursor biosynthesis  
 
|style="background:#ABCDEF;" align="center"|'''Function''' || peptidoglycan precursor biosynthesis  
 
|-
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://cellpublisher.gobics.de/subtiexpress/ ''Subti''Express]''': [http://cellpublisher.gobics.de/subtiexpress/bsu/BSU09670 dat]
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Gene expression levels in [http://subtiwiki.uni-goettingen.de/apps/expression/ ''Subti''Express]''': [http://subtiwiki.uni-goettingen.de/apps/expression/expression.php?search=BSU09670 dat]
 
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/cellwall.html Cell wall]'''
 
|colspan="2" style="background:#FAF8CC;" align="center"| '''Metabolic function and regulation of this protein in [[SubtiPathways|''Subti''Pathways]]: <br/>[http://subtiwiki.uni-goettingen.de/pathways/cellwall.html Cell wall]'''
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|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yheN]]'', ''[[nhaC]]''
 
|style="background:#ABCDEF;" align="center"|'''Immediate neighbours''' || ''[[yheN]]'', ''[[nhaC]]''
 
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|colspan="2" style="background:#FAF8CC;" align="center"|'''Get the DNA and protein [http://srs.ebi.ac.uk/srsbin/cgi-bin/wgetz?-e+&#91;EMBLCDS:CAB12806&#93;+-newId sequences] <br/> (Barbe ''et al.'', 2009)'''
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|style="background:#FAF8CC;" align="center"|'''Sequences'''||[http://bsubcyc.org/BSUB/sequence-aa?type=GENE&object=BSU09670 Protein] [http://bsubcyc.org/BSUB/sequence?type=GENE&object=BSU09670 DNA] [http://bsubcyc.org/BSUB/seq-selector?chromosome=CHROM-1&object=BSU09670 Advanced_DNA]
 
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|colspan="2" | '''Genetic context''' <br/> [[Image:dat_context.gif]]
 
|colspan="2" | '''Genetic context''' <br/> [[Image:dat_context.gif]]

Revision as of 12:27, 13 May 2013

(Another gene coding for O6-methylguanine DNA alkyltransferase was formely known as dat, it is now called ogt)

Gene name dat
Synonyms yheM
Essential no
Product D-alanine aminotransferase
Function peptidoglycan precursor biosynthesis
Gene expression levels in SubtiExpress: dat
Metabolic function and regulation of this protein in SubtiPathways:
Cell wall
MW, pI 31 kDa, 4.871
Gene length, protein length 846 bp, 282 aa
Immediate neighbours yheN, nhaC
Sequences Protein DNA Advanced_DNA
Genetic context
Dat context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
Dat expression.png




























Categories containing this gene/protein

cell wall synthesis, biosynthesis of cell wall components

This gene is a member of the following regulons

The gene

Basic information

  • Locus tag: BSU09670

Phenotypes of a mutant

Database entries

  • DBTBS entry: no entry
  • SubtiList entry: [1]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity: D-alanine + 2-oxoglutarate = pyruvate + D-glutamate (according to Swiss-Prot)
  • Protein family: class-IV pyridoxal-phosphate-dependent aminotransferase family (according to Swiss-Prot)
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure: 1G2W (E177S Mutant, Geobacillus stearothermophilus, 43% identity)
  • KEGG entry: [2]

Additional information

Expression and regulation

  • Operon:
  • Sigma factor:
  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References