Difference between revisions of "GabD"
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| − | + | * '''Description:''' succinate-semialdehyde dehydrogenase (NADP), general stress protein <br/><br/> | |
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|style="background:#ABCDEF;" align="center"|'''Function''' || utilization of gamma-amino butyric acid | |style="background:#ABCDEF;" align="center"|'''Function''' || utilization of gamma-amino butyric acid | ||
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 50 kDa, 4.763 | |style="background:#ABCDEF;" align="center"| '''MW, pI''' || 50 kDa, 4.763 | ||
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|colspan="2" | '''Genetic context''' <br/> [[Image:gabD_context.gif]] | |colspan="2" | '''Genetic context''' <br/> [[Image:gabD_context.gif]] | ||
<div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | <div align="right"> <small>This image was kindly provided by [http://genolist.pasteur.fr/SubtiList/ SubtiList]</small></div> | ||
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__TOC__ | __TOC__ | ||
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<br/><br/> | <br/><br/> | ||
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** [[gabD]] {{PubMed|12123465}} | ** [[gabD]] {{PubMed|12123465}} | ||
| − | * | + | * '''[[Sigma factor]]:''' |
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** ''[[gabT]]'': [[SigA]] {{PubMed|12123465}} | ** ''[[gabT]]'': [[SigA]] {{PubMed|12123465}} | ||
** ''[[gabD]]'': [[SigB]] [http://www.ncbi.nlm.nih.gov/pubmed/15805528 PubMed] | ** ''[[gabD]]'': [[SigB]] [http://www.ncbi.nlm.nih.gov/pubmed/15805528 PubMed] | ||
Revision as of 11:21, 7 August 2012
- Description: succinate-semialdehyde dehydrogenase (NADP), general stress protein
| Gene name | gabD |
| Synonyms | ycnH |
| Essential | no |
| Product | succinate-semialdehyde dehydrogenase (NADP) |
| Function | utilization of gamma-amino butyric acid |
| MW, pI | 50 kDa, 4.763 |
| Gene length, protein length | 1386 bp, 462 aa |
| Immediate neighbours | gabT, glcU |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
| |
Contents
Categories containing this gene/protein
utilization of amino acids, general stress proteins (controlled by SigB)
This gene is a member of the following regulons
The gene
Basic information
- Locus tag: BSU03910
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family:
Extended information on the protein
- Kinetic information:
- Domains:
- Modification:
- Cofactor(s):
- Effectors of protein activity:
Database entries
- Structure: 3RHH (from from Bacillus halodurans C-125 complexed with NADP, 327identity, 68% similarity)
- UniProt: P94428
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Regulation:
- Additional information:
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Dirk Höper, Uwe Völker, Michael Hecker
Comprehensive characterization of the contribution of individual SigB-dependent general stress genes to stress resistance of Bacillus subtilis.
J Bacteriol: 2005, 187(8);2810-26
[PubMed:15805528]
[WorldCat.org]
[DOI]
(P p)
Boris R Belitsky
Bacillus subtilis GabR, a protein with DNA-binding and aminotransferase domains, is a PLP-dependent transcriptional regulator.
J Mol Biol: 2004, 340(4);655-64
[PubMed:15223311]
[WorldCat.org]
[DOI]
(P p)
Boris R Belitsky, Abraham L Sonenshein
GabR, a member of a novel protein family, regulates the utilization of gamma-aminobutyrate in Bacillus subtilis.
Mol Microbiol: 2002, 45(2);569-83
[PubMed:12123465]
[WorldCat.org]
[DOI]
(P p)
A Petersohn, M Brigulla, S Haas, J D Hoheisel, U Völker, M Hecker
Global analysis of the general stress response of Bacillus subtilis.
J Bacteriol: 2001, 183(19);5617-31
[PubMed:11544224]
[WorldCat.org]
[DOI]
(P p)
