Difference between revisions of "YknX"

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|-
 
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|style="background:#ABCDEF;" align="center"|'''Function''' || resistence against [[SdpC]] toxin
 
|style="background:#ABCDEF;" align="center"|'''Function''' || resistence against [[SdpC]] toxin
 +
|-
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|colspan="2" style="background:#FAF8CC;" align="center"| '''Interactions involving this protein in [http://cellpublisher.gobics.de/subtinteract/startpage/start/ ''Subt''Interact]''': [http://cellpublisher.gobics.de/subtinteract/interactionList/2/YknX YknX]
 
|-
 
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|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 41 kDa, 5.178   
 
|style="background:#ABCDEF;" align="center"| '''MW, pI''' || 41 kDa, 5.178   
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* '''[[SubtInteract|Interactions]]:'''
 
* '''[[SubtInteract|Interactions]]:'''
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** [[YknW]]-([[YknX]]-([[YknY]]-[[YknZ]]) {{PubMed|22707703}}
  
* '''[[Localization]]:''' membrane protein
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* '''[[Localization]]:''' membrane protein with a large extracytoplasmic domain  {{PubMed|22707703}}
  
 
=== Database entries ===
 
=== Database entries ===

Revision as of 14:39, 19 June 2012

  • Description: ABC-type antimicrobial peptide transporter (permease) for the export of the SdpC toxin

Gene name yknX
Synonyms
Essential no
Product ABC-type antimicrobial peptide exporter (permease)
Function resistence against SdpC toxin
Interactions involving this protein in SubtInteract: YknX
MW, pI 41 kDa, 5.178
Gene length, protein length 1131 bp, 377 aa
Immediate neighbours yknW, yknY
Get the DNA and protein sequences
(Barbe et al., 2009)
Genetic context
YknX context.gif
This image was kindly provided by SubtiList
Expression at a glance   PubMed
YknX expression.png
























Categories containing this gene/protein

ABC transporters, cell envelope stress proteins (controlled by SigM, V, W, X, Y), resistance against toxins/ antibiotics, membrane proteins

This gene is a member of the following regulons

AbrB regulon, SigW regulon

The gene

Basic information

  • Locus tag: BSU14350

Phenotypes of a mutant

Database entries

  • DBTBS entry: [1]
  • SubtiList entry: [2]

Additional information

The protein

Basic information/ Evolution

  • Catalyzed reaction/ biological activity:
  • Protein family:
  • Paralogous protein(s):

Extended information on the protein

  • Kinetic information:
  • Domains:
  • Modification:
  • Cofactor(s):
  • Effectors of protein activity:

Database entries

  • Structure:
  • KEGG entry: [3]
  • E.C. number:

Additional information

Expression and regulation

  • Regulation:
  • Regulatory mechanism:
  • Additional information:

Biological materials

  • Mutant:
  • Expression vector:
  • lacZ fusion:
  • GFP fusion:
  • two-hybrid system:
  • Antibody:

Labs working on this gene/protein

Your additional remarks

References

Additional publications: PubMed

Bronwyn G Butcher, John D Helmann
Identification of Bacillus subtilis sigma-dependent genes that provide intrinsic resistance to antimicrobial compounds produced by Bacilli.
Mol Microbiol: 2006, 60(3);765-82
[PubMed:16629676] [WorldCat.org] [DOI] (P p)

Qiang Qian, Chien Y Lee, John D Helmann, Mark A Strauch
AbrB is a regulator of the sigma(W) regulon in Bacillus subtilis.
FEMS Microbiol Lett: 2002, 211(2);219-23
[PubMed:12076816] [WorldCat.org] [DOI] (P p)

X Huang, A Gaballa, M Cao, J D Helmann
Identification of target promoters for the Bacillus subtilis extracytoplasmic function sigma factor, sigma W.
Mol Microbiol: 1999, 31(1);361-71
[PubMed:9987136] [WorldCat.org] [DOI] (P p)