Difference between revisions of "SunA"
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{{SubtiWiki category|[[miscellaneous metabolic pathways]]}}, | {{SubtiWiki category|[[miscellaneous metabolic pathways]]}}, | ||
{{SubtiWiki category|[[biosynthesis of antibacterial compounds]]}}, | {{SubtiWiki category|[[biosynthesis of antibacterial compounds]]}}, | ||
| + | {{SubtiWiki category|[[toxins, antitoxins and immunity against toxins]]}}, | ||
{{SubtiWiki category|[[SP-beta prophage]]}}, | {{SubtiWiki category|[[SP-beta prophage]]}}, | ||
{{SubtiWiki category|[[membrane proteins]]}} | {{SubtiWiki category|[[membrane proteins]]}} | ||
Revision as of 08:19, 17 July 2012
- Description: sublancin 168 lantibiotic antimicrobial precursor peptide
| Gene name | sunA |
| Synonyms | yolG |
| Essential | no |
| Product | sublancin 168 lantibiotic antimicrobial precursor peptide |
| Function | antimicrobial peptide |
| MW, pI | 5 kDa, 7.963 |
| Gene length, protein length | 168 bp, 56 aa |
| Immediate neighbours | sunT, sunI |
| Get the DNA and protein sequences (Barbe et al., 2009) | |
Genetic context 
This image was kindly provided by SubtiList
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Expression at a glance PubMed
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Contents
Categories containing this gene/protein
miscellaneous metabolic pathways, biosynthesis of antibacterial compounds, toxins, antitoxins and immunity against toxins, SP-beta prophage, membrane proteins
This gene is a member of the following regulons
Abh regulon, AbrB regulon, Rok regulon, YvrHb regulon
The gene
Basic information
- Locus tag: BSU21480
Phenotypes of a mutant
Database entries
- DBTBS entry: [1]
- SubtiList entry: [2]
Additional information
The protein
Basic information/ Evolution
- Catalyzed reaction/ biological activity:
- Protein family: IPP isomerase type 2 family (according to Swiss-Prot)
- Paralogous protein(s):
Extended information on the protein
- Kinetic information:
- Domains:
- Modification: contains a glucose attached to a cysteine residue, glycosylation is essential for its antimicrobial activity PubMed
- Cofactor(s):
- Effectors of protein activity:
- Localization: cell membrane (according to Swiss-Prot)
Database entries
- Structure:
- UniProt: P68577
- KEGG entry: [3]
- E.C. number:
Additional information
Expression and regulation
- Operon: sunA PubMed
- Sigma factor:
- Regulatory mechanism:
- Additional information: the mRNA is very stable (half-life > 15 min) PubMed
Biological materials
- Mutant:
- Expression vector:
- lacZ fusion:
- GFP fusion:
- two-hybrid system:
- Antibody:
Labs working on this gene/protein
Your additional remarks
References
Additional publications: PubMed
